There are concerns that junior healthcare professionals do not use decision support as they don’t see senior staff using it. There are concerns that seniors don't use clinical decision support as they worry about looking things up people in front of people. So a complex issue to discuss. To find out more about this, listen to this interview with Dr Tom Foley, Consultant Child and Adolescent Psychiatrist with expertise in digital health.

Adhesive capsulitis affects 2% to 5% of the population. It is slightly more common in women than in men, and is most common in people between the ages of 40 and 70. And it can cause a range of problems - including pain, stiffness, and loss of function. So it is important that we get the diagnosis and management of this condition right. To give us more details about this problem and what we can do about it, Kieran Walsh, Clinical Director at BMJ, speaks with Professor Lance LeClerc, Associate Professor of Orthopedic Surgery at Vanderbilt University Medical Centre in Nashville. For more on adhesive capsulitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1043 Competing interests: None

Gastro-oesophageal reflux disease (GORD) is a common condition that affects between 10% and 30% of people in developed countries. There can be a range of complications from haemorrhage to stricture to Barrett's oesophagus. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on GORD, Kieran Walsh talks with Dr Andres Carrion, Associate Professor of Clinical Medicine at The Division of Digestive Health and Liver Diseases in University of Miami Miller School of Medicine. For more on GORD, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/82 Competing interests: None

Snoring is common. In the 30- to 35-year-old age group, 20% of men and 5% of women snore. By 60, 60% of men and 40% of women will snore habitually. And snoring can affect the quality of life - of both the patient and their partner. In this BMJ Best Practice podcast on snoring, Kieran Walsh talks with Dr Showkat Mirza, Consultant in Otorhinolaryngology and Head & Neck Surgery, Sheffield Teaching Hospitals NHS Trust. For more on snoring, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1035 Competing interests: SM has no competing interests

Age-related macular degeneration is the third most common cause of visual impairment worldwide. The main risk is advanced disease and resultant visual loss. Prompt diagnosis and treatment can make a big difference to the outcome - so it is vital that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on macular degeneration, Kieran Walsh talks with Dr. Sajjad Mahmood, Consultant Ophthalmic Surgeon, Medical Retina Specialist, and Honorary Clinical Lecturer at the University of Manchester. For more on age-related macular degeneration, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/554 Competing interests: SM has done consultancy work and received honoraria for lecturing and travel from Bayer Pharmaceuticals and Novartis. He has also been a principal investigator for clinical trials on behalf of Bayer, Novartis, and Roche.

The prevalence of cluster headache is about one in 500. In people coming to a headache clinic, the prevalence is about 10%. Cluster headaches are excruciating and incapacitating, and affect quality of life. Prompt diagnosis and treatment can make a big difference to the outcome - so it is vital that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on cluster headache, Kieran Walsh talks with Professor Amaal Starling, Associate Professor of Neurology at the Department of Neurology in the Mayo Clinic. Further resources: clusterbusters.org/. Competing interests: AS has received consulting fees from AbbVie, Allergan, Amgen, Axsome Therapeutics, Everyday Health, Lundbeck, Med-IQ, Medscape, Neurolief, Satsuma, and WebMD. We release episodes fortnightly.

Spinal cord compression is an extremely serious disorder that can have devastating consequences. These include weakness of the legs, bladder and bowel dysfunction, and loss of sensation. Rapid diagnosis and treatment can make a big difference to the outcome - so it is vital that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on spinal cord compression, Kieran Walsh talks with Professor Kenneth Casey, Clinical Associate Professor in Neurosurgery at Michigan State University and Clinical Associate Professor in Physical Medicine and Rehabilitation at Wayne State University School of Medicine. Competing interests: none declared We release episodes fortnightly.

Halitosis is common and can affect people of all ages. Severe halitosis is less common but it can affect confidence and quality of life. It can even result in social isolation. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on halitosis, Kieran Walsh talks with Professor Stephen Porter, Director of the UCL Eastman Dental Institute in London. Competing interests: none declared

We release episodes fortnightly. Osteoarthritis is the most common form of arthritis. It is more common in women than in men, with incidence increasing sharply around the age of 50. And it can cause complications - including the inability to perform activities of daily living and spinal stenosis in cervical and lumbar osteoarthritis. So it is vital that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on osteoarthritis, Kieran Walsh talks to Fadi Badlissi, Assistant Professor at Harvard Medical School and Director of the Musculoskeletal Medicine Unit at Beth Israel Deaconess Medical Center in Boston. Competing interests: None

We release episodes fortnightly. Data, AI, oncology, and patients are a wide range of subjects to be addressed in one podcast. Individually they are big topics and when you put them together you really get to high levels of complexity. In this BMJ Best Practice podcast, Kieran Walsh delves into all these topics with Dr Arun Sujenthiran, Senior Medical Director and UK Clinical Lead at Flatiron Health. Flatiron Health is a healthtech company that specialises in data science and oncology. Competing interests: AS is an employee of Flatiron Health Inc, an independent subsidiary of Roche, and holds stock in Roche.

We release episodes fortnightly. Stroke is the fourth and fifth leading cause of death in the UK and US, respectively. There are more than 100,000 strokes in the UK every year. And approximately 10% to 15% of all ischaemic strokes are associated with carotid artery stenosis. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on carotid artery stenosis, Kieran Walsh talks to Brajesh Lal, Professor of Vascular Surgery, University of Maryland School of Medicine and Professor of Neurology, Mayo Clinic. Competing interests: None

We release episodes fortnightly. Bell's palsy is the most common unilateral facial palsy in adults. It is most prevalent in people between 15 and 45 years of age. And it can cause a range of complications - including ongoing facial weakness, keratoconjunctivitis sicca, exposure keratopathy, and ectropion. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast, Kieran Walsh talks with Professor Matthew Miller about Bell's palsy. Matt is Assistant Professor Otolaryngology and Head and Neck Surgery, University of North Carolina Chapel Hill. Competing interests: none declared

We release episodes fortnightly. Hypothermia is a serious condition - it can cause rhabdomyolysis, electrolyte disturbances, and cardiac arrhythmias. It can also kill. In the UK, the annual number of hypothermia-related deaths is about 300. And in countries with colder climates, the numbers are far higher. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast, Kieran Walsh talks to Dr Alexander Alexiou, Emergency Medicine Consultant, Barts Health NHS Trust about hypothermia. Competing interests: none declared

We release episodes fortnightly. Rosacea is a common disorder. Studies suggest a prevalence of 5% for women and 4% for men. And rosacea can cause a range of problems including papules and pustules, telangiectasias, and eye problems. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on rosacea, Kieran Walsh talks to Dr Abel Jarell, Dermatologist and Dermatopathologist, Northeast Dermatology Associates, Portsmouth, New Hampshire. Competing interests: none declared

We release episodes fortnightly. Parkinson's disease is a common and serious condition. It is the second most common neurodegenerative disorder in the world - only Alzheimer's disease is more common. And Parkinson's disease can cause a range of complications - from dyskinesias to depression to dementia. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast, Kieran Walsh talks to Delaram Safarpour, Assistant Professor of Neurology at Oregon Health & Science University. Competing interests: DS has received honoraria for participation in advisory boards for Boston Scientific (the manufacturer of Deep Brain Stimulation devices) and Abbvie (the manufacturer of Duopa). She has received consultation fees from Abbott (the manufacturer of Deep Brain Stimulation devices). DS has received an institutional grant and has received an honorarium for lectures from the Parkinson’s Study Group.

Data and big data in healthcare are both important and topical. Big data has the potential to transform how we provide healthcare but can also be problematic. There can be problems with how data is captured, cleaned, and corrected or with how we update data. BMJ is playing an increasing role in this field. We have our own BMJ Data Set which provides AI healthcare technologies with current, credible, and AI-ready content. In this BMJ Best Practice podcast on healthcare and data, Kieran Walsh talks to Professor Dipak Kalra, President of The European Institute for Innovation through Health Data.

Herpes zoster: an update on diagnosis and management The annual incidence of herpes zoster in the UK is between 2 and 4 patients per thousand population. It can cause a range of complications including post-herpetic neuralgia, herpes zoster of the eye, and disseminated zoster. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on herpes zoster, Kieran Walsh talks to Professor Michael Rothberg, Center for Value-Based Care Research, Cleveland Clinic, Cleveland, Ohio. MR declares that he has no competing interests.- The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Status epilepticus is a serious medical emergency. Fortunately, it is relatively rare but when it does occur it can cause a range of serious complications including focal neurological deficits, cognitive dysfunction, and behavioural problems. So it is important that we get the diagnosis and management of this condition right. In this BMJ Best Practice podcast on status epilepticus, Kieran Walsh talks to Dr. Rajiv Mohanraj, Consultant Neurologist and Honorary Senior Lecturer at the Manchester Centre for Clinical Neurosciences - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Acute pancreatitis: an update on diagnosis and management Acute pancreatitis is a common and serious condition. The incidence of acute pancreatitis in the UK is about 50 per 100,000 per year. And it can cause a range of complications including acute renal failure, pancreatic abscess and of course chronic pancreatitis. So it is important that we get diagnosis and management of this condition right. In this BMJ Best Practice podcast on acute pancreatitis, Kieran Walsh talks to Professor Scott Tenner, Clinical Professor of Medicine, State University of New York. ST is an author of references cited in the BMJ Best Practice topic on acute pancreatitis. He declares that he has no other competing interests. BMJ Relevant topic link - https://bestpractice.bmj.com/topics/en-gb/3000118 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

COPD or chronic obstructive pulmonary disease is common. The pooled global prevalence is 15% in men and 9% in women. The expanding epidemic of smoking and the ageing of the population means that its prevalence is increasing. And COPD is a serious disease. It is associated with recurrent pneumonia, cor pulmonale, and respiratory failure. In this BMJ Best Practice podcast, Kieran Walsh talks to Dr. Hanna Sandelowsky, GP, Head of Unit at the Academic Primary Healthcare Centre, and Senior Researcher at Karolinska Institutet in Sweden. - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Transient ischemic attacks are common - in the UK, the US and around the world. And they are important – mainly because of the high risk of stroke following a TIA. The risk of stroke is high in the first 7 days. So it is important to get on with diagnosis, investigations, and management as soon as possible. In this BMJ Best Practice podcast, Kieran Walsh talks to Dr Jennifer Simpson, Vascular Neurologist and Associate Professor in the Department of Neurology at the University of Colorado. - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Atrial fibrillation is the most common sustained heart rhythm disorder in adults worldwide. The prevalence is between 2% and 4%. If left untreated, atrial fibrillation is a significant risk factor for stroke, myocardial infarction and congestive cardiac failure. So it is important that we get diagnosis and management of this condition right. In this BMJ Best Practice podcast on new-onset atrial fibrillation, Kieran Walsh talks to Bharat Kantharia, Clinical Professor of Medicine, Icahn School of Medicine at Mount Sinai, New York. - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Axial spondyloarthritis is a chronic progressive inflammatory arthropathy, which ultimately may lead to radiographical changes in the spine and sacroiliac joints. This radiographical stage is known as ankylosing spondylitis. Inflammatory back pain is the hallmark clinical feature. This is defined as back pain that is of insidious onset, is worse in the morning, and improves with exercise. In this podcast, Markku Kauppi, Professor of Rheumatology, Helsinki University, gives a clinical overview of the condition. For more on ankylosing spondylitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/366 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Ischaemic stroke is a leading cause of morbidity and mortality. The World Health Organization defines stroke as “a clinical syndrome consisting of rapidly developing clinical signs of focal (or global) disturbance of cerebral function, lasting more than 24 hours or leading to death, with no apparent cause other than that of vascular origin”. David Wang, Professor of Neurology, Barrow Neurological Institute, Phoenix, Arizona, gives us a clinical overview of the condition. For more on ischaemic stroke, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000114 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Essential tremor is characterised by a progressive tremor of the upper extremities, present in posture and action, without other neurological signs or symptoms. The prevalence and incidence increases with age, but the condition can appear in early adulthood in those who have a family history. Sheng-Han Kuo, Assistant Professor of Neurology, Columbia University, New York, gives us an overview of the condition. For more on essential tremor, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1089 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Patients with asthma present with recurrent episodes of shortness of breath, chest tightness, wheezing, or coughing. Examination typically demonstrates an expiratory wheeze; however, in severe asthma there is poor air entry and the chest is silent. Lauren Eggert, Clinical Assistant Professor, Division of Pulmonary, Allergy, and Critical Care Medicine, Stanford University School of Medicine, gives us a clinical overview of the condition. For more on asthma, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/44 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Bacterial meningitis represents a life-threatening inflammation of the meninges. Elisabeth Adderson, Associate Member, St. Jude Faculty, Director, Pediatric Infectious Diseases Fellowship Program, St. Jude Children's Research Hospital, Memphis, gives an overview of the condition. For more on bacterial meningitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000104 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Type 1 diabetes mellitus is a metabolic disorder characterised by hyperglycaemia due to absolute insulin deficiency. The condition develops due to destruction of pancreatic beta cells, mostly by immune-mediated mechanisms. In this podcast, Rajesh Garg, Professor of Medicine, University of Miami Miller School of Medicine, gives us an overview of the condition. For more on type 1 diabetes, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/25 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Generalised anxiety disorder (GAD) is a common condition defined as chronic, excessive worry for at least six months that causes distress or impairment. Christopher Gale, Research Director and Consultant Psychiatrist, Southern District Health Board, New Zealand gives a clinical overview of the condition. For more on GAD, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/120 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Lyme disease is an infectious disease transmitted to humans through the bite of infected ticks. Erythema migrans develops at the site of tick bite usually within 1 to 2 weeks and is a pathognomic feature. Constitutional symptoms such as fever, headache, myalgias, fatigue, and arthralgias may occur. In this podcast, Janak Koirala, Professor of Medicine and Infectious Diseases, Division of Infectious Diseases, Southern Illinois University School of Medicine, gives us an overview of the condition. For more on lyme disease, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/224 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Jet lag and sleep phase disorders affect millions of travellers worldwide. Rapid change in time zone produces a constellation of symptoms called jet lag disorder. Symptoms include difficulty initiating and maintaining sleep, reduced daytime alertness, general malaise, and gastrointestinal symptoms. In this podcast, Ashish Adlakha, Assistant Clinical Professor, Neurology and Sleep Medicine, Connecticut Healthcare, gives us a clinical overview. For more on jet lag, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1017 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Post-traumatic stress disorder may develop (either immediately or delayed) following exposure to a stressful event or situation of an exceptionally threatening or catastrophic nature. According to DSM-5, it is characterised by 4 groups of symptoms: intrusion symptoms, avoidance, negative alterations in cognition and mood, and alterations in arousal and reactivity. These symptoms must impair function for a diagnosis to be made. In this podcast, Mathew Hoskins, Consultant Psychiatrist and Clinical Teaching Fellow, Cardiff University, gives us a clinical overview of the disorder. For more on PTSD, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/430 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic congestive heart failure is a complex clinical syndrome that can result from any structural or functional cardiac disorder that impairs the ability of the ventricle to fill with or eject blood. It is a major and growing public health problem. In this podcast, Syed Wamique Yusuf, FACC, FRCPI Syed Wamique Yusuf, Professor of Medicine, Department of Cardiology, University of Texas MD Anderson Cancer Center, gives a clinical overview of the condition. For more on chronic congestive heart failure, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/61 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to Covid-19. Abigail Davis, GP and section editor, covers the latest evidence around vaccine immunogenicity in different immunosuppressed populations, as well as the use of interleukin-6 inhibitors in COVID-19 patients. And Emma Scott, section editor, updates us on mucormycosis, or black fungus infection in COVID-19 patients. For more, see: BMJ Best Practice's topic on COVID-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning COVID-19 in primary care module: new-learning.bmj.com/course/10065230 Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00676-0/fulltext Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19: https://www.nejm.org/doi/full/10.1056/NEJMoa2100433 WHO Therapeutics and COVID-19: living guideline: https://app.magicapp.org/#/guideline/nBkO1E/section/LrV7OL Indian Council of Medical Research advice on mucormycosis: https://www.icmr.gov.in/pdf/covid/techdoc/Mucormycosis_ADVISORY_FROM_ICMR_In_COVID19_time.pdf

Persistent depressive disorder is a category that includes various forms of chronic depression in which depressive symptoms are present 'more days than not' over at least a 2-year period (1 year in children and adolescents). David J. Hellerstein, Professor of Clinical Psychiatry, Columbia University Medical Center, gives us a clinical overview of the condition. For more on persistent depressive disorder, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/805 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic sinusitis is inflammation of the paranasal sinuses lasting more than 12 weeks. Symptoms include facial pressure, rhinorrhoea, postnasal drainage, congestion, and general malaise. Raj Sindwani, Section Head of Rhinology, Sinus, and Skull Base Surgery, Head and Neck Institute, Cleveland Clinic Foundation, gives us a clinical overview of the condition. For more on chronic sinusitis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/15 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Bulimia nervosa is an eating disorder, characterised by severe preoccupation about weight and body shape. Includes recurrent episodes of binge eating with compensatory mechanisms, such as self-induced vomiting, to prevent weight gain. Debra Safer, Associate Professor, Co-Director of Stanford Eating and Weight Disorders Program, Stanford University School of Medicine, gives us an overview of the condition. For more on bulimia nervosa, see BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/441 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Giant cell arteritis is a common form of vasculitis in people aged 50 years or older. The extracranial branches of the carotid artery are usually affected. Kenneth J. Warrington, Professor of Medicine, Mayo Clinic College of Medicine, gives us an overview of the condition. For more on giant cell arteritis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/177 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Emma Scott, section editor, updates us on vaccination for pregnant and breastfeeding women. And Abigail Davis, GP and section editor, covers myocardial infarction and pre-existing respiratory conditions. For more, see: BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Emma Scott, section editor, updates us on vaccination and the risk of blood clots. And Abigail Davis, GP and section editor, covers acute kidney injury, venous thromboembolism prevention, and secondary bacterial pneumonia. For more, see: BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 EMA: ema.europa.eu/en/news/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood MHRA: gov.uk/government/news/mhra-issues-new-advice-concluding-a-possible-link-between-covid-19-vaccine-astrazeneca-and-extremely-rare-unlikely-to-occur-blood-clots JCVI: gov.uk/government/publications/use-of-the-astrazeneca-covid-19-vaccine-jcvi-statement/jcvi-statement-on-use-of-the-astrazeneca-covid-19-vaccine-7-april-2021 WHO: who.int/news/item/07-04-2021-interim-statement-of-the-covid-19-subcommittee-of-the-who-global-advisory-committee-on-vaccine-safety COVID-19 rapid guideline: managing COVID-19: nice.org.uk/guidance/NG191 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Depression can describe both a mood and an illness. Major depressive disorder is a clinical syndrome involving mood, neurovegetative functions, cognition, and behaviour. It affects 5% to 10% of patients in the primary care setting. Dean F. MacKinnon, Associate Professor, Psychiatry and Behavioral Sciences, The Johns Hopkins Hospital, Baltimore, gives us an overview of how to diagnose and manage depression in adults. For more on depression in adults, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/55 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Childhood constipation is typically characterised by infrequent bowel evacuations, large stools, and difficult or painful defecation. Symptoms may result from low fibre, poor nutrient, and/or insufficient water intake, which leads to excessive hardening of the stool. This often starts as an acute problem but can progress to faecal impaction and chronic constipation. Claire Zar-Kessler, Instructor in Pediatric Gastroenterology, Massachusetts General Hospital for Children, Boston gives us a clinical overview of the condition. Please always check the licensed indications for medications in your own country. For more on constipation in children, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/784 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Raynaud's phenomenon (RP) is characterised by vasospasm that causes digits to change colour to white (pallor) from lack of blood flow, usually brought on by cold temperatures. Affected areas subsequently turn blue due to de-oxygenation and/or red due to reperfusion. It can be a painful condition and can lead to complications. Janet Pope, Professor of Medicine, Division of Rheumatology, Department of Medicine, University of Western Ontario, gives a clinical overview of the condition. For more on Raynaud's phenomenon, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/193 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Chronic kidney disease (CKD) is a common condition that is often unrecognised until the most advanced stages. The most common causes are diabetes mellitus and hypertension. Manisha Singh, Assistant Professor, Division of Nephrology, Department of Internal Medicine, University of Arkansas for Medical Sciences, gives us an overview of the condition. For more, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/84 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden, GP and section editor, updates us on pulse oximetry, prognostic scoring, and management in hospital. And Abigail Davis, GP and section editor, covers Covid-19 vaccination and chronic conditions, including advice for patients with thrombocytopenia, and those taking immunosuppressive drugs, ACE inhibitors or ARBs. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning's quick tips module: proning in critical care: learning.bmj.com/learning/modules/elucidat/10065419 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230

Depression in children is characterised by sad or irritable mood, anhedonia, decreased capacity to have fun, decreased self-esteem, sleep disturbance, social withdrawal or impaired social relationships, and impaired school performance. It is one of the most common paediatric psychiatric disorders, especially among girls during adolescence. David A. Brent, Endowed Chair in Suicide Studies, Professor of Psychiatry, Pediatrics, Epidemiology, and Clinical and Translational Science, University of Pittsburgh, gives us an overview of the condition. For more on depression in children, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/785 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden, GP and section editor, updates us on vaccination and long covid-19. And Abigail Davis, GP and section editor, covers Covid-19 and comorbidities, namely endocrine conditions and bronchiolitis. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 JCVI independent report published by the Department of Health: www.gov.uk/government/publications/prioritising-the-first-covid-19-vaccine-dose-jcvi-statement/optimising-the-covid-19-vaccination-programme-for-maximum-short-term-impact Online covid-19 recovery platform: www.yourcovidrecovery.nhs.uk

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden, GP and section editor, updates us on vaccination and the use of remdesivir. And Emma Scott, section editor, covers Covid-19 and comorbidities, namely COPD, learning disabilities and obesity. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 UK Gov guidance on covid vaccinations: gov.uk/government/publications/covid-19-vaccination-programme-guidance-for-healthcare-practitioners UK Gov Green Book covid chapter: gov.uk/government/publications/covid-19-the-green-book-chapter-14a - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Asthma exacerbations present with acute or sub-acute onset of wheeze and respiratory distress, the symptoms and signs of which vary depending on the developmental and maturational age of the child. Triggers include viral or bacterial infection, inhaled allergens, environmental irritants, emotion, medications, and poor adherence with preventive therapy. Paul D. Robinson, Respiratory and Sleep Physician, The Children's Hospital at Westmead and Associate Professor, Discipline of Paediatrics and Child Health, University of Sydney, gives a clinical overview of acute asthma exacerbations in children. For more on acute asthma exacerbations in children, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1098 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

A recent meta-analysis by Espinosa and colleagues, “Prevalence of Comorbidities in Patients and Mortality Cases Affected by SARS-CoV2”, found that 42% of patients with Covid-19 had comorbidities. Furthermore, 61% of those with Covid-19 admitted to the Intensive Care Unit had comorbidities, and 77% of those who died had comorbidities. Hypertension was the most prevalent comorbidity (affecting 32% of patients). Other common comorbidities included diabetes (22%), heart disease (13%), and COPD (8%). In this podcast Andrew Lewington, Consultant Renal Physician and Honorary Clinical Associate Professor, St James’s University Hospital, Leeds, gives us an overview of managing patients with Covid-19 and common comorbidities. For more on Covid-19 and comorbidities, see BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000201/treatment-algorithm Read the meta analysis: Espinosa OA, Zanetti ADS, Antunes EF, Longhi FG, Matos TA, Battaglini PF. Prevalence of comorbidities in patients and mortality cases affected by SARS-CoV2: a systematic review and meta-analysis. Rev Inst Med Trop Sao Paulo. 2020;62:e43. Published 2020 Jun 22. doi:10.1590/S1678-9946202062043

Gestational diabetes develops during pregnancy and is usually diagnosed at 24 to 28 weeks of gestation on the basis of elevated plasma glucose levels on glucose tolerance testing. The goal of therapy is to achieve maternal glucose levels that are as close to normal as possible in order to avoid fetal macrosomia and complications. Chloe Zera, Assistant Professor, Harvard Medical School gives us a clinical overview of the condition. For more on gestational diabetes, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/665 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks Matt Castleden, GP and editor for BMJ Best Practice and BMJ Learning, to summarise the latest clinical guidance in acute medicine. Dr Castleden updates us on recent recommendations on pulmonary embolism, and also acute respiratory distress and vaping associated lung injury. For more information, take a look at the BMJ Best Practice topic on pulmonary embolism: bestpractice.bmj.com/topics/en-gb/3000115 The BMJ Best Practice topic on acute respiratory distress syndrome: bestpractice.bmj.com/topics/en-gb/374

Colonic diverticulosis refers to herniation of the mucosa and submucosa through the muscular layer of the colonic wall and may be the result of colonic smooth muscle over-activity. Diverticular disease may be defined as any clinical state caused by symptoms pertaining to colonic diverticula and includes a wide-ranging spectrum from asymptomatic to severe and complicated disease. Mohamed Thaha, Senior Lecturer & Lead Consultant in Colorectal Surgery, National Bowel Research Centre, Barts and The London School of Medicine and Dentistry, tells us more. For more on diverticular disease, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/16 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden updates us on the clinical use of antibody testing. And Abigail Davis discusses the impact of the pandemic on other conditions, including mental health and other infectious diseases. She also covers recommendations for influenza vaccination. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 BMJ Practice Pointer article: Testing for SARS-CoV-2 antibodies: bmj.com/content/370/bmj.m3325 WHO guidance on Diagnostic testing for SARS-CoV-2: who.int/publications/i/item/diagnostic-testing-for-sars-cov-2 CDC Interim guidance on antibody testing: cdc.gov/coronavirus/2019-ncov/lab/resources/antibody-tests-guidelines.html CDC Influenza vaccination: cdc.gov/flu/professionals/acip/index.htm Public Health England annual flu programme: gov.uk/government/collections/annual-flu-programme Royal College of Paediatrics and Child Health advice for parents and carers: rcpch.ac.uk/sites/default/files/2020-04/covid19_advice_for_parents_when_child_unwell_or_injured_poster.pdf

Anaphylaxis is a severe, generalised or systemic hypersensitivity reaction. It is characterised by rapidly developing life-threatening airway and/or breathing and/or circulation problems usually associated with skin and mucosal changes. Adriana Andreae, Assistant Professor, Department of Pediatrics Division of Allergy and Immunology, Penn State University, gives us an overview of the condition. For more on anaphylaxis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000099 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden updates us on treatment with steroids, PPE and symptoms of covid-19 which are present weeks or months after infection. And Emma Scott talks about surveys on the mental health of populations during the pandemic. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): new-learning.bmj.com/course/10065100 BMJ Learning covid-19 in primary care module: new-learning.bmj.com/course/10065230 Public Health England: COVID-19: mental health and wellbeing surveillance report: gov.uk/government/publications/covid-19-mental-health-and-wellbeing-surveillance-report Mental Health, Substance Use, and Suicidal Ideation During the COVID-19 Pandemic — United States: cdc.gov/mmwr/volumes/69/wr/mm6932a1.htm

End of life care is specialised medical care for people with serious illness that focuses on the best quality of life for both the patient and their family. Oliver Minton, Macmillan Consultant, Brighton and Sussex University Hospital, Brighton, UK, gives us an overview of best practice in this area. For more on end of life care, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1020 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Fibromyalgia patients typically present with chronic, widespread body pain and almost always have accompanying comorbid symptoms such as fatigue, memory difficulties, and sleep and mood difficulties. Physical examination is typically normal but there is often diffuse tenderness. Daniel Clauw, Professor of Medicine, Division of Rheumatology, University of Michigan Health System, Ann Arbor, gives us a clinical overview of the condition. For more on fibromyalgia, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/187 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden updates us on self-isolation and shielding, and resources for people recovering from Covid-19. Abigail Davis discusses new evidence on the impact of Covid-19 on emergency department attendances and hospital admissions, as well as new guidance on planned care. And Emma Scott covers the link between weight and Covid-19. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-…oduleId=10065100 BMJ Learning covid-19 in primary care module: learning.bmj.com/learning/module-…oduleId=10065230 NICE: arranging planned care in hospitals and diagnostic services https://www.nice.org.uk/guidance/ng179 Decrease in emergency department attendances during lockdown: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2768777?guestAccessKey=b9b4b5e0-5e42-4801-ae4f-6e8aa6a904b2&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=080320 Decrease in hospital admissions during lockdown: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31356-8/fulltext Reduced rates of cancer diagnosis: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2768946

Deep vein thrombosis (DVT) is the development of a blood clot in a major deep vein in the leg, thigh, pelvis, or abdomen, which may result in impaired venous blood flow and consequent leg swelling and pain. Scott C. Woller, Director, Thrombosis Clinic, Intermountain Medical Center, Murray and Professor of Medicine, University of Utah, gives us an overview of the condition. For more on DVT, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/70 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Abigail Davis discusses the latest guidance on ADHD and renal transplant patients care. And Matt Castleden updates us on care for covid-19 patients post discharge. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): https://learning.bmj.com/learning/module-intro/.html?moduleId=10065100 BMJ Learning covid-19 in primary care module: learning.bmj.com/learning/module-intro/.html?moduleId=10065230 NICE renal transplant guidelines: nice.org.uk/guidance/NG178 European ADHD guidelines group recommendations: thelancet.com/pdfs/journals/lanchi/PIIS2352-4642(20)30110-3.pdf NHS England: After-care needs of inpatients recovering from COVID-19: england.nhs.uk/coronavirus/publication/after-care-needs-of-inpatients-recovering-from-covid-19/

Chest pain is a common chief complaint. It may be caused by either benign or life-threatening aetiologies and is usually divided into cardiac and non-cardiac causes. James E. Brown, Professor and Chair, Wright State University Boonshoft School of Medicine, Kettering, Ohio, gives us an overview of assessing chest pain in the emergency setting. For more on assessing chest pain, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/301 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Emma Scott discusses the latest guidance on cardiovascular disease. And Matt Castleden updates us on NHS Test and Trace, shielding, and social distancing. He also covers the news on dexamethasone as a treatment for covid-19. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-intro/.html?moduleId=10065100 ESC guidelines: escardio.org/Education/COVID-19-and-Cardiology/ESC-COVID-19-Guidance WHO on smoking and covid-19: who.int/publications/i/item/smoking-and-covid-19 Recovery trial news page: recoverytrial.net/news/low-cost-dexamethasone-reduces-death-by-up-to-one-third-in-hospitalised-patients-with-severe-respiratory-complications-of-covid-19 MHRA and NHS alert on dexamethasone: cas.mhra.gov.uk/ViewandAcknowledgment/ViewAlert.aspx?AlertID=103054 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Patients with anorexia nervosa typically have low body weight, intense fear of gaining weight, and a body image disturbance. In this podcast Evelyn Attia, Professor of Psychiatry, Columbia University and Weill Cornell Medical College, New York, gives a clinical overview of the condition. For more on anorexia nervosa, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/440 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Abigail Davis talks about advice for patients with osteoporosis, and also those with migraine. Emma Scott discusses the latest guidance on HIV. And Matt Castleden updates us on covid-19 management. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-…oduleId=10065100 European Society of Endocrinology - Osteoporosis guideline: eje.bioscientifica.com/view/journals/eje/aop/eje-20-0385/eje-20-0385.xml European Acamdey of Neurology - advice for managing patients with migraine: eanpages.org/2020/04/09/headache-in-covid-19-pandemic-2/ US Department of Health and Human Science, Interim Guidance for COVID-19 and Persons with HIV: aidsinfo.nih.gov/guidelines/html/8/covid-19-and-persons-with-hiv--interim-guidance-/0 British HIV Association, Statement on risk of COVID-19 for people living with HIV: bhiva.org/EACS-BHIVA-statement-on-risk-of-COVID-19-for-people-living-with-HIV-PLWH

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Abigail Davis talks about advice for patients with chronic kidney disease. Emma Scott discusses the latest guidance on interstitial lung disease. And Matt Castleden updates us on covid-19 testing for healthcare workers. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-…oduleId=10065100 NICE COVID-19 rapid guideline: interstitial lung disease: nice.org.uk/guidance/ng177 COVID-19: management of exposed staff and patients in health and social care settings: gov.uk/government/publications/covid-19-management-of-exposed-healthcare-workers-and-patients-in-hospital-settings NICE COVID-19 rapid guideline: chronic kidney disease: nice.org.uk/guidance/NG176

Schizophrenia onset is usually in early adulthood and may be preceded by years of ill-differentiated symptoms, from behavioural changes and delusions to frank psychosis. Initially, patients are usually referred by family members. As the illness progresses, patients tend to self-refer or are brought in by a case manager or law enforcement officer. Antipsychotic therapy and psychosocial interventions are effective for most patients, but to varying degrees. Adrian Preda, Professor of Clinical Psychiatry, Department of Psychiatry and Human Behavior, University of California, Irvine School of Medicine, tells us more about the condition. For more on schizophrenia, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/406 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Matt Castleden covers dermatological manifestations of covid-19. Emma Scott discusses the latest guidance on CPR. And Abigail Davis talks about advice for newborn care. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-intro/.html?moduleId=10065100 International Liaison Committee on Resuscitation: ilcor.org/covid-19 Interim Guidance for Life Support for COVID-19 (from the US): ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.120.047463 Resuscitation Council UK Statements on COVID-19 (Coronavirus), CPR and Resuscitation: resus.org.uk/media/statements/resuscitation-council-uk-statements-on-covid-19-coronavirus-cpr-and-resuscitation/ Royal College of Paediatrics and Child Health Guidance for Neonatal Care: rcpch.ac.uk/resources/covid-19-guidance-neonatal-settings Resuscitation Council UK COVID-19 resources Newborn Life Support: resus.org.uk/media/statements/resuscitation-council-uk-statements-on-covid-19-coronavirus-cpr-and-resuscitation/covid-19-resources-nls/ American Academy of Pediatrics Managements of Infants born to Mothers with COVID-19: downloads.aap.org/AAP/PDF/COVID%2019%20Initial%20Newborn%20Guidance.pdf

Irritable bowel syndrome symptoms include recurrent abdominal pain or discomfort that is associated with a change in stool frequency or form. The pain or discomfort may be relieved by defecation. Ned Synder, Chief of Gastroenterology and Hepatology, Kelsey-Seybold Clinic and Clinical Professor of Medicine, Baylor College of Medicine, Houston gives us an overview of the condition. For more on IBS, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/122 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

In this podcast, Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clincial guidance related to covid-19. Emma Scott covers the latest on routine immunisation. Abigail Davis discusses advice on thromboembolism and advice on mental health care for healthcare workers. And Matt Castleden summarises the current standing on contact tracing. For more, see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-intro/covid-19-nice-guidelines.html?moduleId=10065100 PHE contact tracing letters: gov.uk/government/publications/contact-tracing-letter-to-directors-of-public-health Emergency Responders: tips for taking care of yourself: emergency.cdc.gov/coping/responders.asp NHS England Clinical Guide for the Management of Anticoagulant Services during the coronavirus pandemic: england.nhs.uk/coronavirus/wp-content/uploads/sites/52/2020/03/C0077-Specialty-guide_Anticoagulant-services-and-coronavirus-v1-31-March.pdf WHO Guiding principles for immunization activities during the COVID-19 pandemic: apps.who.int/iris/handle/10665/331590 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Atrial fibrillation is chaotic and irregular atrial arrhythmia, the prevalence of which increases progressively with age. It causes significant morbidity and death. Many patients are asymptomatic or have symptoms that are less specific for cardiac arrhythmias, such as mild dementia or silent strokes. Gregory Lip, Price-Evans Chair of Cardiovascular Medicine, University of Liverpool, gives us an overview of the condition. For more on atrial fibrillation, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

In our new weekly podcast, Kieran Walsh, clinical director at BMJ, asks editors from BMJ Best Practice and BMJ Learning to summarise how clinical guidance is changing in response to covid-19. Matt Castleden discuss the latest advice on PPE and testing, and also an alert on an acute, atypical presentation of covid-19 in children. Abigail Davis summarises advice on palliative care, and on IBD. And Emma Scott covers guidance on perinatal care. For more, please see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Best Practice's topic on covid-19: bestpractice.bmj.com/topics/en-gb/3000168 BMJ Learning module on COVID-19 rapid guideline on critical care (NICE): learning.bmj.com/learning/module-intro/resume-module.html? Paediatric Intensive Care Society statement: Increased number of reported cases of novel presentation of multisystem inflammatory disease: picsociety.uk/wp-content/uploads/2020/04/PICS-statement-re-novel-KD-C19-presentation-v2-27042020.pdf RCPCH position statement: Delayed access to care for children during COVID-19: rcpch.ac.uk/resources/delayed-presentation-during-covid-19-positionmoduleId=10065100 BMJ Best Practice Palliative Care: bestpractice.bmj.com/topics/en-gb/1020/details NICE COVID-19 rapid guideline: symptoms management (including end of life care) in the community: nice.org.uk/guidance/ng163 NICE COVID-19 rapid guideline: gastrointestinal and liver conditions treated with drugs that affect the immune response: nice.org.uk/guidance/NG172 RCOG guidelines: Coronavirus (COVID-19) infection and pregnancy: rcog.org.uk/en/guidelines-research-services/guidelines/coronavirus-pregnancy ACOG guidelines on covid-19: www.acog.org/topics/covid-19 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

In our new weekly podcast, Kieran Walsh, clinical director at BMJ, asks editors from BMJ Best Practice and BMJ Learning to summarise how clinical guidance is changing in response to covid-19. Abigail Davis discuss the latest advice on rheumatological conditions, and that on prescribing contraception. Emma Scott covers new guidance for managing COPD in the community, and also for the use of nebulisers. And Suchita Shah talks about RCGP and BMA advice on prioritising GP workload. For more, please see: BMJ Best Practice's topic on management of coexisting conditions in the context of COVID-19: bestpractice.bmj.com/topics/en-gb/3000190 BMJ Learning module on prescribing contraception in primary care; learning.bmj.com/learning/module-intro/ask-an-expert-contraception.html?moduleId=10055243 NICE COVID-19 rapid guideline: rheumatological autoimmune, inflammatory and metabolic bone disorders: nice.org.uk/guidance/ng167 American College of Rheumatology COVID-19 Clinical guidelines: rheumatology.org/Announcements#ClinicalGuidance British Society for Rheumatology COVID-19 guidance for rheumatologists: rheumatology.org.uk/News-Policy/Details/Covid19-Coronavirus-update-members Faculty of Sexual and Reproductive Healthcare COVID-19 resources: fsrh.org/fsrh-and-covid-19-resources-and-information-for-srh/ American College of Obstetricians and Gynecologists COVID-19 resources: acog.org/en/Topics/COVID-19 NICE COVID-19 rapid guideline: community-based care of patients with COPD: www.nice.org.uk/guidance/ng168 BTS COVID-19: information for the respiratory community: brit-thoracic.org.uk/about-us/covid-19-information-for-the-respiratory-community GOLD Covid-19 guidance: goldcopd.org/gold-covid-19-guidance RCGP GP workload prioritisation guideline: rcgp.org.uk/covid-19/latest-covid-19-guidance-in-your-area.aspx - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

In this podcast, editors from BMJ Best Practice and BMJ Learning cover this week's major covid-19 clinical updates. Matt Castleden and Abigail Davis, both Section Editors at BMJ Best practice and BMJ Learning, discuss the latest guidelines on PPE, clinical frailty scoring, silent hypoxia, and community-acquired pneumonia. The RCP state that NEWS2 should be used when managing patients with COVID 19: rcplondon.ac.uk/news/news2-and-deterioration-covid-19 Read the NICE pneumonia guidance here: nice.org.uk/guidance/ng165 For more on Covid-19, look at BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/3000168 Or find relevant BMJ Learning content here: new-learning.bmj.com/covid-19 Currently this content is available for free. - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Tension-type headaches can be either episodic or chronic. They are rarely disabling or associated with any significant autonomic phenomena, thus patients do not usually seek medical care and usually successfully self-treat. Unlike migraine, there is no significant nausea, no vomiting, and a lack of aggravation by routine physical activity. In this podcast Mark Green, Professor of Neurology, Anesthesiology and Rehabilitation Medicine, Director of Headache and Pain Medicine, Icahn School of Medicine at Mount Sinai, New York, gives a clinical overview of the condition. For more on tension headache, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/12 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Rheumatoid arthritis is a chronic, erosive arthritis that requires early and aggressive treatment. In this podcast, Yusuf Yazici, Clinical Associate Professor of Medicine, New York University School of Medicine, gives us a clinical overview of the condition. For more on rheumatoid arthritis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/105 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Osteoporosis is a complex skeletal disease characterised by low bone density and micro-architectural defects in bone tissue, resulting in increased bone fragility and susceptibility to fracture. In this podcast, Opinder Sahota, Professor of Orthogeriatric Medicine & Consultant Physician, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, gives a clinical overview of the condition. For more on osteoporosis, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/85 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Suicide is not inevitable. Most people experiencing suicidal thoughts are ambivalent about dying but may be unable to imagine other potential solutions. With the right support people can find their way through a suicidal crisis and recover. In this podcast, Alys Cole-King, Clinical Director 4Mental Health and Consultant Liaison Psychiatrist, Glan Clwyd Hospital, Wales, talks us through managing those with suicidal thoughts, and why we need a paradigm shift in suicide risk assessment that moves away from ‘characterising, predicting, and managing risk’ towards ‘compassion, safeguarding, and safety planning’. For more on suicide risk management, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1016 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Adult attention deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder presenting with inattentiveness, impulsivity, and hyperactivity, persisting into adulthood. It is characterised primarily by inner restlessness rather than hyperactivity; impatience; sensation seeking and excessive spending rather than impulsivity; inattention; and functional impairment with underachievement and disorganisation. Marios Adamou, Consultant Psychiatrist, South West Yorkshire NHS Partnership Foundation Trust, University of Huddersfield gives us a clinical overview of the condition. For more on ADHD in adults, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/814 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Postnatal depression refers to a depressive illness following childbirth and may form part of a unipolar or, less frequently, a bipolar illness. Ian Jones, Professor of Psychiatry, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, gives us an overview of the condition. For more on postnatal depression, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/512 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Hypertension is a common disorder that affects a large proportion of the community. It is usually asymptomatic and is detected on routine examination or after the occurrence of a complication such as a heart attack or stroke. In this podcast Gregory Lip, Price-Evans Professor of Cardiovascular Medicine, University of Liverpool, UK, and Senior Investigator, National Institute for Health Research, UK, gives up an overview of the condition. For more on hypertension, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1071 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Heart failure is a complex clinical syndrome resulting from the impaired ability of the heart to cope with the metabolic needs of the body, resulting in breathlessness, fatigue, and fluid retention. Approximately half of patients with heart failure have normal, or near-normal, left ventricular ejection fraction and are classified as having heart failure with preserved ejection fraction. Gerald Carr-White, Consultant Cardiologist, Guys and St Thomas’ NHS Foundation Trust, UK, gives us an overview of the condition. For more on heart failure with preserved ejection fraction, see BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/953 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Crimean-Congo haemorrhagic fever (CCHF)is a notifiable condition, and outbreaks have occurred in Asia, Africa, and Southeast Europe. It resents as a sudden-onset, severe illness with initial influenza-like symptoms, red eyes, and petechiae leading to signs of haemorrhage around day 4. In this podcast, Tom Fletcher, Wellcome Trust/MoD Research Fellow, Liverpool School of Tropical Medicine, UK, gives us a clinical overview of the virus. For more on CCHF see BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1606 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Alzheimer's disease is a chronic neurodegenerative disease with an insidious onset and progressive but slow decline. It is the most common type of dementia. Judith Neugroschl, Assistant Professor of Psychiatry, Mount Sinai School of Medicine, New York, gives us a clinical overview of the disease. For more on Alzheimer's, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/317 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

According to NICE, two thirds of people aged 65 or over have more than one medical condition, and 47% have three or more. Martin Cowie, Professor of Cardiology, Imperial College London, discusses how comorbidities are a big problem for the health service, and how they should be approached. For more on BMJ Best Practice's Comorbidities Tool, see bestpractice.bmj.com/info/comorbidities - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Crohn's disease is a condition is a disorder of unknown aetiology, with common presenting symptoms including chronic diarrhoea, weight loss, and right lower quadrant abdominal pain mimicking acute appendicitis. Georgia Woodfield, SpR in Gastroenterology and General Medicine, Imperial College Healthcare NHS Trust, gives us an overview of the condition. For more on Crohn's disease, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/42 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Characterised by upper and lower respiratory tract symptoms of rhinorrhoea, cough, fever, chills, headache, and myalgia, influenza can occur in local community outbreaks, epidemics, and, rarely, pandemics. Kanta Subbarao, Director of the WHO Collaborating Centre for Reference and Research on Influenza, Peter Doherty Institute for Infection and Immunity, Melbourne, Australia, gives us a clinical overview of the infection. For more on influenza, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/6 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Ron Behrens, Consultant in Tropical and Travel Medicine, Hospitals for Tropical Diseases and Senior Lecturer, London School of Hygiene and Tropical Medicine, gives us a clinical overview of malaria. For more on malaria visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/161 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Anthrax is a rare infection caused by the spore-forming, gram-positive soil organism Bacillus anthracis . Cutaneous disease is the most common manifestation; however, fatal systemic illness due to spore ingestion, inhalation, or injection can occur. In this podcast Ali Hassoun, Infectious Disease Specialist, Alabama Infectious Diseases Center, USA, gives us a clinical overview of anthrax. For more on anthrax, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/604 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Coeliac disease is common, affecting up to 1% of the general population, and has a varied presentation. Matthew Kurien, Senior Clinical Lecturer and Honorary Consultant Gastroenterologist, Department of Infection, Immunity & Cardiovascular Disease, Sheffield Medical School, gives us a clinical overview of the disease. For more on coeliac disease, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/636 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Botulism is a paralytic illness caused by the neurotoxin produced by Clostridium botulinum, and it is most commonly seen in infants. In this podcast Linda Nield, Professor of Pediatrics, West Virginia University School of Medicine, talks us through how to recognise and manage the condition. For more on botulism, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/810 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Jodi Antonelli, Assistant Professor, Department of Urology, University of Texas Southwestern Medical Center, gives us a clinical overview of nephrolithiasis. For more on nephrolithiasis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/225 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Fadi Badlissi, Assistant Professor, Harvard Medical School, and Director of the Musculoskeletal Medicine Unit, Beth Israel Deaconess Medical Center, Boston, gives us a clinical overview of gout. For more on gout, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/13 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Venezuelan equine encephalitis is a mosquito-borne virus, endemic to Central and South America. It usually causes mild and self-limiting disease in humans, however CNS infection can lead to long-term neurological sequelae and death, particularly in children. In this podcast we get a clinical overview of the disease, from Stalin Vilcarromero, Assistant Professor and Clinical Research Scientist, Department of Medicine, Stony Brook University, New York, USA. For more on Venezuelan equine encephalitis virus, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1614 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Nigel Cowley is a GP from the Denmark Road Medical Centre in Bournemouth, UK, with a special interest in mental health, and in this podcast he shares his advice on, and experiences of, assessing, managing and treating patients with anxiety and depression. For more on anxiety and depression, visit BMJ Learning: learning.bmj.com - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Pregnancy in women living with HIV is complicated not only by HIV infection itself but also by the medical and psychosocial comorbidities associated with HIV. Prof Rachel Scott, Scientific Director of Women’s Health Research for MedStar Health Research Institute, and Assistant Professor in Obstetrics and Gynaecology, Georgetown University, gives us a clinical overview of caring for pregnant women with HIV. For more on HIV in pregnancy, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/556 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Henipavirus is a rare, but emerging, infection in the Asia-Pacific region. An outbreak of Nipah virus infection was reported in India in May 2018, but was quickly contained. Catherine Houlihan, Clinical Lecturer at University College London London, gives us a clinical overview of the disease. For more on henipavirus, see BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/1607 - The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Global trends in the estimated number of drug users (2009 to 2014) indicate that the use of opioids, including the use of heroin and opium, and the non-medical use of pharmaceutical opioids, has stabilised at high levels. Worldwide, around 35.1 million people are estimated to have used opioids in 2016. How can clinicians recognise and manage those misusing opioids? Here to offer advice is Prof Jonathan Lee, Medical Director at The Farley Center at Williamsburg Place, Williamsburg, US. For more on opioid use disorder, visit Best Practice: bestpractice.bmj.com/topics/en-gb/200 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

This week, we're joined by Sian Griffiths, Emeritus Professor at the Chinese University of Hong Kong, Visiting Professor at Imperial College London, and Chair of the Public Health England Global Health Committee. Professor Griffiths discusses the 2002-2003 SARS outbreak in Hong Kong, and what healthcare professionals should know about the virus. For more on SARS, visit BMJ Best Practice: newbp.bmj.com/topics/en-gb/904 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Alissa Willis, Staff Neurologist in the Neurological Institute's Mellen Center for Multiple Sclerosis, Cleveland Clinic, gives us a clinical overview of multiple sclerosis. For more on multiple sclerosis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/140 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Sudhakar Selvaraj, assistant professor of psychiatry at the University of Texas Health Science Centre, gives us a clinical overview of bipolar disorder. For more on bipolar disorder, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/488 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

We know that infectious disease outbreaks are caused by pathogens, but some would argue that they are also a biological manifestation of social inequality. Here to discuss the politics of disease outbreak, and how this informs how the global community should respond to them, is Simukai Chigudu, Associate Professor of African Politics and Fellow of St Antony's College, Oxford University. To find out more about BMJ's Global Health initiatives, visit: bmj.com/company/global-health-ii

What is glanders, and how do you recognise, refer and report it? Dr Robert Norton, Director of Microbiology, Townsville Hospital, Australia, gives us the answers. For more information on Glanders, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1601 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Prof Tim Collins, Associate Professor of Neurology, Duke University Medical Center, USA, gives us a clinical overview of migraine. For more on migraine, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/10 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Prof Mike Morgan, National Clinical Director Respiratory NHS England, gives us a clinical guide to COPD. To learn more about COPD, visit BMJ Learning: Managing acute exacerbations of COPD in primary care - bit.ly/2sQPK1R Chronic obstructive pulmonary disease: diagnosis and assessment of severity - bit.ly/2TdNgpU Chronic obstructive pulmonary disease: long term management - bit.ly/2FSYAoj Spirometry in practice - bit.ly/2RQ6ntD _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Dr Jacob A Lebin, Emergency Medicine Resident, University of Washington, Harborview Medical Center, gives a clinical guide to marine toxins poisoning. To learn more about marine toxins poisoning, visit BMJ Best Practice. https://bestpractice.bmj.com/topics/en-gb/1605 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

South American haemorrhagic fevers are a group of five highly dangerous and highly infectious diseases. Professor Thomas Ksiazek, Professor of Pathology, University of Texas Medical Branch, Galveston, US, talks us through how to recognise, refer and report these fevers. For more information on South American haemorrhagic fevers, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/1612 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Prof David Dance, senior clinical research fellow and consultant microbiologist, Lao-Oxford-Mahosot Hospital, Vientiane, Laos, gives us a clinical overview of melioidosis. For more information on melioidosis, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1601 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Dr Jonathan Quick, author of 'The End of Epidemics: The Looming Threat to Humanity and How to Stop It', discusses the threat of epidemics and pandemics, and how they can be prevented. To learn more about epidemics and pandemics, visit BMJ Best Practice. bestpractice.bmj.com _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Learn how to recognise, refer and report Poxvirus infection, with Dr Thomas Blanchard, Consultant in Infectious Diseases, Department of Infectious Diseases and Tropical Medicine, Royal Liverpool Hospital. During a poxvirus outbreak there may be many potential contacts most of whom can be managed by passive surveillance by public health authorities. A symptomatic contact needs to be a risk assessed as most do not need to be seen in full personal protective equipment in a regional infectious diseases unit. For example, a close household contact who develops fever and rash is at high risk, whereas someone who happens to live in the same city and has a fever but no rash is at very low risk. To learn more about Poxvirus, visit BMJ Best Practice. bestpractice.bmj.com/topics/en-gb/1611 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Lisa Bebell, Instructor in Medicine, Massachusetts General Hospital, and who conducts research in to infectious diseases and critical care medicine, gives us a clinical guide to Marburg Virus. To learn more about Marburg Virus, visit BMJ Best Practice. bestpractice.bmj.com/topics/en-gb/1615 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

In this podcast, Rakesh Patel, Clinical Associate Professor in Medical Education and Honorary Consultant Nephrologist at the University of Nottingham, talks us through making a diagnosis in the context of infectious diseases. For more information, visit BMJ Best Practice: bestpractice.bmj.com _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

This podcast is a clinical guide to abrin poisoning, with Scott Phillips, Associate Clinical Professor of Medicine, Clinical Pharm & Toxicology, University of Colorado - Denver. To learn more about abrin poisoning, visit BMJ Best Practice: bestpractice.bmj.com/topics/en-gb/1051 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Clayton Willey, Professor of Pathology,
 UPMC Presbyterian Hospital Division of Neuropathology, Pittsburgh, USA, talks us through the recognition, referral and reporting of Rift Valley Fever. To learn more about Rift Valley Fever, visit BMJ Best Practice: https://bestpractice.bmj.com/topics/en-gb/1602 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

A clinical guide to viral haemorrhagic fevers in children, with Nathalie MacDermott, Wellcome Clinical Research Training Fellow, Imperial College London. To learn more about viral haemorrhagic fevers, visit BMJ Best Practice. bestpractice.bmj.com/topics/en-gb/1210 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

How to recognise, refer and report Lassa fever, with John Schieffelin, Assistant Professor of Medicine & Pediatrics, Tulane University School of Medicine, New Orleans. To learn more about Lassa Fever, visit BMJ Best Practice. https://bestpractice.bmj.com/topics/en-gb/1609 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Susan Smolinske, Director of the New Mexico Drug and Poison Information Centre, and Professor of Pharmacy Practice and Administrative Sciences, University of New Mexico, gives us a clinical guide to ricin poisoning. To learn more about ricin poisoning, visit BMJ Best Practice. bestpractice.bmj.com/topics/en-gb/1051 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

A clinical guide to Brucellosis, with Drs Nick Beeching, Senior Lecturer Clinical Infectious Diseases, and Alessandro Gerada, Medical Microbiology Trainee, both at the Liverpool School of Tropical Medicine. To learn more about Brucellosis, visit BMJ Best Practice. https://bestpractice.bmj.com/topics/en-gb/911 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

International travel is increasingly common. Between 10% and 42% of travellers to any destination, and 15%-70% of travellers to tropical settings experience ill health, either while abroad or on returning home, Malaria is the commonest specific diagnosis, accounting for 5%-29% of all individuals presenting to specialist clinic, followed by dengue, enteric fever, and rickettsial infections . In this podcast Doug Fink specialist registrar, and Victoria Johnston consultant, in infectious diseases at The Hospital for Tropical Diseases join us to discuss diagnosis, and treatment - and why the clinically most interesting diagnosis is rarely the right one. Read the full practice article: www.bmj.com/content/360/bmj.j5773 This podcast was produced by The BMJ. _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Dr Mary-Margaret Fill currently works as a Medical Epidemiologist in Communicable and Environmental Diseases and Emergency Preparedness at the Tennessee Department of Health. To learn more about Avian Influenza, visit BMJ Best Practice. http://bestpractice.bmj.com/topics/en-gb/455 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Christopher Paddock, Medical Officer and pathologist in the Rickettsial Zoonoses Branch in CDC’s Division of Vector-Borne Diseases, gives a clinical guide to recognising and managing typhus group rickettsiae. For more on typhus group rickettsiae, take a look at Best Practice: http://bestpractice.bmj.com/topics/en-gb/1604 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

A clinical guide to recognising and managing Tularaemia. Dr Isaac Bogoch is a clinical researcher, Toronto General Hospital Research Institute, Canada. To learn more about Tularaemia Infection, visit BMJ Learning https://goo.gl/7kRgeu And BMJ Best Practice bestpractice.bmj.com/topics/en-gb/916 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Dr. Matthieu Million is a Senior Lecturer and Hospital Practitioner at the Infectious Diseases Unit, Centre Expert du Microbiote Humain, in Marseille, France. To learn more about Coxiella Burnetii Infection, visit BMJ Best Practice (http://bestpractice.bmj.com/topics/en-gb/1139) and BMJ Learning (http://learning.bmj.com) _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Hypertension: everything you need to know about the new 2017 AHA/ACC guidelines This podcast covers the implications of the new 2017 ACC/AHA guidelines for clinicians and their patients, including changes to the definition of hypertension, self monitoring, management and new recommendations in relation to existing guidelines. Dr Jeffrey Brettler is a general internist who practices at the Kaiser Permanente West Los Angeles Medical Center and is the author of the BMJ Best Practice topic, Essential Hypertension. Dr Brettler is interviewed by Dr Alison Walker, a Clinical Editor for BMJ Best Practice and BMJ Learning. To learn more about Hypertension, visit BMJ Best Practice (bestpractice.bmj.com/topics/en-gb/26). 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults (acc.org/guidelines#doctype=Guidelines) _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Plague - a guide to diagnosing and managing Yersinia Dr. Amesh Adalja is a Senior Scholar at the Johns Hopkins University Center for Health Security. He also serves on the City of Pittsburgh’s HIV Commission. He is board certified in internal medicine, emergency medicine, infectious diseases, and critical care medicine. To learn more about Yersinia Infection, visit BMJ Best Practice (http://bestpractice.bmj.com/topics/en-gb/1156). _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Botulism: a guide to recognition, reporting and referral - with Dr Claudia Kraft Dr Claudia Kraft, MD, CCFP (EM), MSc, is an emergency physician, formerly a full-service family physician. She has practiced in the Canadian Arctic/subarctic for her entire medical career, first in Iqaluit, Nunavut and now in Yellowknife, Northwest Territories (where she lives with her partner Steve, their son Henry, and their husky). To learn more about Botulism, visit BMJ Best Practice (https://bestpractice.bmj.com/topics/en-gb/810). _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

BMJ Clinical Director Dr Kieran Walsh speaks with Dr Tom Fletcher (http://www.lstmed.ac.uk/about/people/dr-tom-fletcher) about Ebola infection. Dr Tom Fletcher is a Wellcome Trust/Ministry of Defence Research Training Fellow and an Infectious Diseases Speciality Registrar in Liverpool. He is a physician in the Defence Medical Services and his research is on investigating the pathogenesis of Crimean-Congo Haemorrhagic Fever. He is specifically interested in viral haemorrhagic fevers and, during a recent secondment with the World Health Organisation, was deployed to West Africa to help with the Ebola outbreak. Here are links to studies and guidelines that were referred to. Ebola: Technical guidance documents for medical staff from the World Health Organisation (WHO)- http://www.who.int/csr/disease/ebola/protective-measures-staff/en/. Implementing an Ebola Vaccine Study — Sierra Leone - https://www.cdc.gov/mmwr/volumes/65/su/pdfs/su6503a14.pdf. Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe - http://www.nejm.org/doi/full/10.1056/NEJMoa1502924. To learn more about Ebola Virus Infection, visit BMJ Best Practice (http://bestpractice.bmj.com/best-practice/monograph/1210.html). _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Following acute exposure to the hepatitis C virus, most people develop chronic infection that increases the risk for long-term hepatic complications. Current treatment with oral direct-acting agents aims to eradicate the virus. Jawad Ahmad, Professor of Medicine in the Division of Liver Diseases at The Mount Sinai Hospital in New York, discusses hepatitis C infection with BMJ Knowledge Centre's U.S. Clinical Lead Sheila Feit, including future directions for a rapidly evolving field. More information available at the BMJ Best Practice website: http://bestpractice.bmj.com. About BMJ Best Practice BMJ Best Practice takes you quickly and accurately to the latest evidence based information, whenever and wherever you need it. Our step by step guidance on diagnosis, prognosis, treatment and prevention is updated daily using robust evidence based methodology and expert opinion. We support you in implementing good practice. Sign up to a free 7 day trial here*: bestpractice.bmj.com/info/subscribe/free-trial/ The below topics will be made freely available for 2 weeks from World Hepatitis Day (28th July 2017): Hepatitis C Step-by-step management: http://bestpractice.bmj.com/best-practice/monograph/128/treatment/details.html Treatment guidelines including American Association for the Study of Liver Diseases (AASLD) and European Association for Study of the Liver (EASL) http://bestpractice.bmj.com/best-practice/monograph/128/treatment/guidelines.html Hepatitis C Clinical Update in The BMJ (free access until 10th August 2017) http://www.bmj.com/content/358/bmj.j2861 *Please note that free personal trials and personal subscriptions are not available in North America. _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

Most people with chronic hepatitis B infection are asymptomatic, but long-term complications may include cirrhosis, hepatocellular carcinoma, or liver failure. Jawad Ahmad, Professor of Medicine in the Division of Liver Diseases at The Mount Sinai Hospital in New York, discusses hepatitis B virus infection with BMJ Knowledge Centre's U.S. Clinical Lead Sheila Feit, including how to approach diagnostic serologies and treatment to help reduce the risk of advanced liver disease. More information available at the BMJ Best Practice website: http://bestpractice.bmj.com. About BMJ Best Practice BMJ Best Practice takes you quickly and accurately to the latest evidence based information, whenever and wherever you need it. Our step by step guidance on diagnosis, prognosis, treatment and prevention is updated daily using robust evidence based methodology and expert opinion. We support you in implementing good practice. Sign up to a free 7 day trial here*: bestpractice.bmj.com/info/subscribe/free-trial/ The below topics will be made freely available for 2 weeks from World Hepatitis Day (28th July 2017): Hepatitis B Diagnostic investigations: http://bestpractice.bmj.com/best-practice/monograph/127/diagnosis/tests.html Hepatitis B Step-by-step management: http://bestpractice.bmj.com/best-practice/monograph/127/treatment/details.html Treatment guidelines including American Association for the Study of Liver Diseases (AASLD) and European Association for Study of the Liver (EASL) http://bestpractice.bmj.com/best-practice/monograph/127/treatment/guidelines.html *Please note that free personal trials and personal subscriptions are not available in North America. _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

A BMJ Clinical Evidence systematic overview looks at the evidence for medical and surgical treatments of trigeminal neuralgia, and the uncertainties that exist due to gaps in the evidence. This has been summarised in The BMJ. The authors of the overview and bmj.comsummary, Prof. Joanna Zakrzewska from the Facial Pain Unit at the Eastman Dental Hospital, London, and Mark Linskey, Professor of Neurological Surgery at the University of California Irvine, discuss the evidence, the issues around it, and put this all into a clinical context. Read the full systematic overview: http://clinicalevidence.bmj.com/x/systematic-review/1207/overview.html Disclaimer: The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others. BMJ does not warrant the accuracy of the information contained in the podcast and to the fullest extent permitted by law, BMJ Publishing Group Limited is not responsible for any loss whatsoever resulting from the application of, or reliance upon, the information contained in this podcast.