Bivalent mRNA COVID-19 vaccines were recommended for children and adolescents aged 5 to 17 years in the US, but were they effective? JAMA Associate Editor Tracy A. Lieu, MD, MPH, spoke with author Leora R. Feldstein, PhD, US Centers for Disease Control and Prevention, about the effectiveness of bivalent COVID-19 vaccines in children and adolescents. Related Content: Effectiveness of Bivalent mRNA COVID-19 Vaccines in Preventing SARS-CoV-2 Infection in Children and Adolescents Aged 5 to 17 Years

The COVID-19 pandemic has caused major disruptions in ambulatory care. In this interview with JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, Rishi K. Wadhera, MD, MPP, MPhil, of Harvard Medical School discusses how access to care and preventive services changed for different racial and ethnic groups in the US from 2019 to 2022. Related Content: Changes in Health Care Access and Preventive Health Screenings by Race and Ethnicity

Two recent studies find that COVID-19 vaccination during pregnancy is safe for infants and effective for children aged 1-4 years. JAMA Pediatrics Editor in Chief Dimitri Christakis, MD, and JAMA Pediatrics Associate Editor Alison Galbraith, MD, discuss clinical and policy implications with Grace Lee, MD, MPH, professor of Pediatrics at Stanford University School of Medicine, Palo Alto, California. Related Content: Newborn and Early Infant Outcomes Following Maternal COVID-19 Vaccination During Pregnancy Effectiveness of Monovalent mRNA Vaccines Against Omicron XBB Infection in Singaporean Children Younger Than 5 Years

During the COVID-19 pandemic, the incidence of diabetes in childhood increased. JAMA Associate Editor Anne R. Cappola, MD, ScM, and Ezio Bonifacio, PhD, from the Center for Regenerative Therapies at the Dresden University of Technology, discuss SARS-CoV-2 infection and its association with islet autoimmunity in early childhood. Related Content: SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood

Interview with Jay F. Piccirillo, MD, author of Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction: The GRACE Randomized Clinical Trial. Hosted by Paul C. Bryson, MD, MBA. Related Content: Efficacy of Gabapentin For Post–COVID-19 Olfactory Dysfunction

In this interview, JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, explore with Erin K. McCreary, PharmD, and Atheendar S. Venkataramani, MD, PhD, how a large regional health system used a weighted lottery and intensive outreach to provide high-risk individuals in disadvantaged communities more equitable access to scarce monoclonal antibodies for preventing COVID-19. Related Content: Weighted Lottery to Equitably Allocate Scarce Supply of COVID-19 Monoclonal Antibody Moving Beyond Intent and Realizing Health Equity

JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, discuss with Sandra B. Nelson, MD (Massachusetts General Hospital, Boston), her JAMA Health Forum study of transmission of SARS-CoV-2 in schools in Massachusetts during 2 different phases of the COVID-19 pandemic. She found transmission rates were very low but varied by district and the availability of vaccines. Related Content: Prevalence and Risk Factors for School-Associated Transmission of SARS-CoV-2

Interview with Rishi P. Singh, MD, author of Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data. Hosted by Neil Bressler, MD. Related Content: Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data

The COVID-19 pandemic has disrupted health care in many domains, including mental health services. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Ryan K. McBain, PhD, MPH, of RAND Corporation how the use of mental health care—both in-person and telehealth visits—changed for commercially insured adults during the first year of the COVID-19 pandemic in 2020.

Interview with Matthew S. Durstenfeld, MD, MAS, and Priscilla Y. Hsue, MD, authors of Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults: A Systematic Review and Meta-analysis. Hosted by Angel N. Desai, MD, MPH. Related Content: Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults

In July 2022, Nahid Bhadelia, MD, MALD, joined the White House COVID-19 Response Team as senior policy advisor for Global COVID Response. The infectious disease physician, who is on sabbatical from Boston University, spoke with JAMA Associate Managing News Editor Jennifer Abbasi about the pandemic’s true burden of disease in low- and middle-income countries and ongoing COVID-19 vaccine inequity. Related Content: White House Advisor Nahid Bhadelia, MD, MALD, on COVID-19 in Resource-Limited Nations—Undercounted Deaths, Vaccine Inequity, and More Global COVID-19 Update (video)

Early in the COVID-19 pandemic, most states approved temporary regulatory changes so out-of-state physicians could provide telemedicine services to residents. Ateev Mehrotra, MD, of Harvard Medical School, and Chad Ellimoottil, MD, MS, of the University of Michigan, speak with JAMA Health Forum Editor John Ayanian, MD, and Deputy Editor Melinda Buntin, PhD, about the features of telemedicine visits provided for Medicare beneficiaries across state borders during the first year of the pandemic and potential policy changes that would enable such visits to continue.   Related Content: Receipt of Out-of-State Telemedicine Visits Among Medicare Beneficiaries During the COVID-19 Pandemic Takeaways From 2 Key Studies on Interstate Telehealth Use Among Medicare Fee-for-Service Beneficiaries

On August 3, 2022, the US Department of Health and Human Services released 2 major reports in response to a presidential memo calling for a whole-of-government response to the SARS-CoV-2 sequelae known as “Long COVID." JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, discusses these new reports and the research and support needed to address this pervasive health concern with HHS Assistant Secretary for Health Rachel Levine, MD. Recorded July 29, 2022. Related Content: Addressing the Long-term Effects of COVID-19 Association Between BNT162b2 Vaccination and Long COVID After Infections Not Requiring Hospitalization in Health Care Workers Long COVID: The US Federal Response (Video)

Interview with Elizabeth M. Harry, author of Childcare Stress, Burnout, and Intent to Reduce Hours or Leave the Job During the COVID-19 Pandemic Among US Health Care Workers.Hosted by Angel N. Desai, MD, MPH.

Interview with Paolo Boffetta, MD, author of Global Association of COVID-19 Pandemic Measures With Cancer Screening: A Systematic Review and Meta-analysis. Hosted by Jack West, MD.

What a Post–Roe v Wade US Might Look Like for Physicians; SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus Related Article(s): What a Post–Roe v Wade US Might Look Like for Physicians SARS-CoV-2 RNA Can Persist in Stool Months After Respiratory Tract Clears Virus

As the White House’s COVID-19 Response Coordinator, Ashish Jha, MD, MPH, plays a critical role in the federal government’s continued response to the pandemic. In this Q&A with JAMA Associate Editor Preeti Malani, MD, Jha details current thinking and federal planning around additional boosters, testing trends, and treatment for COVID-19. Related Content: New White House COVID-19 Leader on What’s Next Q&A With White House COVID-19 Response Coordinator Ashish Jha

Interview with Peter Watkinson, MD, and Julia Hippisley-Cox, MD, authors of Neuropsychiatric Ramifications of Severe COVID-19 and Other Severe Acute Respiratory Infections. Hosted by John Torous, MD, MBI.

Misinformation about COVID-19 (such as around vaccines, masks, and ineffective drugs) has circulated widely during the pandemic, and much of this misinformation is protected by the Free Speech Clause of the First Amendment. Professor of Surgery and Perioperative Care and Professor of Law William M. Sage, MD, JD, from the University of Texas at Austin, is interviewed in this JAMA podcast. Related Content: Reducing “COVID-19 Misinformation” While Preserving Free Speech

Interview with Cheng-Ying Ho, MD, PhD, author of Postmortem Assessment of Olfactory Tissue Degeneration and Microvasculopathy in Patients With COVID-19. Hosted by Cynthia E. Armand, MD.

The health care workforce has yet to recover from the COVID-19 pandemic, and there is a concerning trend of increasing numbers of physicians leaving the workforce. JAMA Health Forum Editor John Ayanian, MD, MPP, and Deputy Editor Melinda Buntin, PhD, discuss with Bianca Frogner, PhD, of the University of Washington new findings that show how all segments of the health care workforce have struggled, with more pronounced effects among long-term care workers, aides, assistants, workers with young children, and workers of color. Related Content: Tracking Turnover Among Health Care Workers During the COVID-19 Pandemic US Health Care Workforce Changes During the COVID-19 Pandemic Changes in Material Hardship During the First Year of the COVID-19 Pandemic

Interview with Michael Springer, PhD, and Andrew Bo Liu, authors of Association of COVID-19 Quarantine Duration and Postquarantine Transmission Risk in 4 University Cohorts Hosted by Angel N. Desai, MD, MPH.

Interview with Ilana Doweck, MD, author of Association Between the BNT162b2 Messenger RNA COVID-19 Vaccine and the Risk of Sudden Sensorineural Hearing Loss, and Eric J. Formeister, MD, MS, author of Assessment of Sudden Sensorineural Hearing Loss After COVID-19 Vaccination Hosted by Joseph P. Bradley, MD.

Pregnant and recently pregnant individuals who become infected with the COVID-19 virus are at high risk of requiring extra medical care. JAMA Associate Editor Linda Brubaker, MD, MS, from University of California San Diego discusses the rapidly evolving data around COVID-19 and vaccine effectiveness and safety as it relates to pregnancy, breastfeeding, and fertility with 3 experts in the field: Laura E. Riley, MD, from Weill Cornell Medicine, Christina Chambers, PhD, MPH, from University of California San Diego School of Medicine-Pediatrics, and Denise Jamieson, MD, MPH, from Emory University. Related Content: COVID-19 and Pregnancy COVID-19 Vaccination During Pregnancy: Maternal Protection and Neonatal Immunity Widespread Misinformation About Infertility Continues to Create COVID-19 Vaccine Hesitancy Conflict of Interest Disclosures: Dr Chambers reported receiving research funding from Pfizer-BioNTech to study the safety of its COVID-19 vaccine in pregnancy. Dr Jamieson reported no disclosures. Dr Riley reported receiving compensation from UpToDate for work on several infections disease cards, receiving royalties from Turner Publishing, and serving on an advisory board for Maven. Dr Riley also reported serving on a CDC Advisory Committee on Immunization Practices workgroup on COVID-19 vaccines and vaccine safety and workgroups for the American College of Obstetricians and Gynecologists and Society for Maternal-Fetal Medicine of COVID-19 vaccination, without compensation.

For the duration of the COVID-19 pandemic public health emergency, state Medicaid programs elected to maintain eligibility for Medicaid recipients in exchange for increased federal funding. In this podcast, Dr Laura Dague of the Bush School of Government & Public Service at Texas A&M University discusses her JAMA Health Forum article finding that this policy was associated with the higher Medicaid enrollment seen during the pandemic. JAMA Health Forum Editor John Ayanian and Deputy Editor Melinda Buntin discuss the policy implications of this work with Dr Dague and other recent articles touching on Medicaid enrollment. Related Content: Trends in Medicaid Enrollment and Disenrollment Early in the COVID-19 Pandemic in Wisconsin Medicaid Disenrollment After the COVID-19 Pandemic Medicaid Coverage Disruptions Among Children Enrolled in North Carolina Medicaid, 2016-2018 Association of Medicaid Expansion in Arkansas With Postpartum Coverage, Outpatient Care, and Racial Disparities

Interview with Steven Woloshin, MD, MS, author of At-Home Self-Testing Kits for SARS-CoV-2: A Randomized Trial Assessing How Consumers Interpret and Act on Possible Test Results. Hosted by Deborah Grady, MD, MPH.

Interview with Walter S. Gilliam, PhD, and Thomas S. Murray, MD, PhD, authors of Association of Child Masking With COVID-19–Related Closures in US Childcare Programs. Hosted by Angel Desai, MD.

Three members of President Biden’s former COVID-19 Advisory Board—Luciana Borio, MD, Ezekiel Emanuel, MD, PhD, and Mike Osterholm, PhD—discuss their recent JAMA Viewpoints, providing their ideas on strategies for public health as COVID-19 transitions from pandemic to endemic. Hosted by JAMA Associate Editor Preeti Malani, MD. Related Content: A National Strategy for the “New Normal” of Life With COVID A National Strategy for COVID-19—Testing, Surveillance, and Mitigation Strategies A National Strategy for COVID-19 Medical Countermeasures Former Biden-Harris Transition Advisors Propose a New National Strategy for COVID-19 Public Health in an Era of Endemic COVID-19 (video)

Former CDC Executive Secretariat of the Advisory Committee on Immunization Practices Amanda Cohn, MD, joins JAMA Associate Editor Preeti Malani, MD, for the latest on the need for vaccination and boosters, vaccine misinformation, and tackling the pandemic from a global perspective. Recorded January 6, 2022. Related Content: One Year of COVID-19 Vaccines: A Shot of Hope, a Dose of Reality COVID-19 Vaccines Have Been Available in the US for More Than a Year—What’s Been Learned and What’s Next? COVID-19 CDC Update – Early January 2022

Infectious disease experts Adam Lauring, MD, PhD, and Carlos del Rio, MD, join JAMA Associate Editor Preeti Malani, MD, MSJ, for a discussion of the newly emerged Omicron variant, the potential for a 2021-2022 "twindemic" with flu, and the latest COVID-19 clinical updates. Recorded December 1, 2021. Related content: Omicron Has Reached the US—Here’s What Infectious Disease Experts Know About the Variant COVID-19 Update: Omicron Variant

Interview with Cédric Lemogne, MD, PhD, and Joane Matta, PhD, authors of Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic. Hosted by Mitchell H. Katz, MD. Read Transcript

COVID-19 Crisis Advances Efforts to Reimagine Nursing Homes; Moving COVID-19 Testing Out of the Clinic and Into the Home; The Lingua Franca of Addiction—Stigmatizing Words That Wound Related Content: COVID-19 Crisis Advances Efforts to Reimagine Nursing Homes COVID-19 Testing Moves Out of the Clinic and Into the Home The Lingua Franca of Addiction—Stigmatizing Words That Wound

Interview with Alex C. Spyropoulos, author of Efficacy and Safety of Therapeutic-Dose Heparin vs Standard Prophylactic or Intermediate-Dose Heparins for Thromboprophylaxis in High-risk Hospitalized Patients With COVID-19: The HEP-COVID Randomized Clinical Trial

The longstanding shortcomings of the US nursing home model became more visible during the COVID-19 crisis. Terry Fulmer, PhD, RN, a geriatric nurse practitioner and president of the John A. Hartford Foundation in New York City, discusses the challenges skilled nursing facilities face and shares her vision for nursing homes that better serve residents and support the workforce. Related Content: COVID-19 Crisis Advances Efforts to Reimagine Nursing Homes Socially Assistive Robots Help Patients Make Behavioral Changes

Canadian law gives the country’s individual provinces and territories primary responsibility for coronavirus containment and mitigation. JAMA Associate Editor Preeti Malani, MD, MSJ, from the University of Michigan and Allan S. Detsky, MD, PhD, from the University of Toronto, Ontario, Canada, discuss the national pandemic experience, including public health responses to infection and vaccine allocation, from fall 2020 through summer 2021. Related Content: COVID-19 in Canada: Experience and Response to Waves 2 and 3

Interview with Grayson W. Armstrong, MD, MPH, author of Association of Patient Characteristics With Delivery of Ophthalmic Telemedicine During the COVID-19 Pandemic, and Fasika Ambachew Woreta, MD, MPH, author of Analysis of Sex Diversity Trends Among Ophthalmology Match Applicants, Residents, and Clinical Faculty

Many patients experience neurocognitive deficits, PTSD, and generalized weakness and disability following an intensive care unit (ICU) stay. JAMA Medical News Senior Writer Rita Rubin talks with E. Wesley Ely, MD, MPH, a professor of medicine at Vanderbilt University School of Medicine, about ICU aftereffects, post-acute COVID-19 syndrome, and how the coronavirus pandemic, particularly hospitals’ restrictions on visitors, impeded progress made since the 1990s in caring for the critically ill. Related Content: How COVID-19 Made It Even Tougher to Know ICU Patients as Individuals

We know that the pandemic caused millions of people to lose their jobs, and potentially their job-based insurance, and yet new survey data showed surprisingly small changes in uninsurance rates at the end of 2020. Kate Bundorf, PhD, from the Sanford School of Public Policy at Duke University and Jessica Banthin, PhD, of the Urban Institute talk to JAMA Health Forum Deputy Editor Melinda Buntin about these trends and the role played by Medicaid and exchange coverage. JAMA Health Forum Editor John Ayanian and Melinda Buntin also discuss other recent work about health insurance coverage and the ACA that has appeared in JAMA Health Forum. Related Content: Trends in US Health Insurance Coverage During the COVID-19 Pandemic Fewer People May Have Become Uninsured in 2020 Than Feared Outcomes After Changes to US Health Insurance Marketplace Automatic Renewal Rules Income Eligibility for Medicaid vs Marketplace Coverage for Insurance Enrollment Among Low-Income Adults Making the Affordable Care Act Marketplace More Affordable

Interview with Alexander T. Hillel, M.D., author of Quantifying Viral Particle Aerosolization Risk During Tracheostomy Surgery and Tracheostomy Care Related Content: Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic

The COVID-19 pandemic has had far-reaching effects on the use of health care services. Dr Nora Becker of the University of Michigan talks about her research on reductions in the use of women’s preventive health services, and JAMA Health Forum Editors Dr John Ayanian and Dr Melinda Buntin discuss other JAMA Health Forum pieces on the effects of state “reopenings” on COVID-19 hospitalizations and deaths, the effects of day care closures on women’s participation in the labor force, and news about nursing home outbreaks of COVID-19. Related Content: Utilization of Women’s Preventive Health Services During the COVID-19 Pandemic CDC Estimates Thousands of Excess Deaths Among US Patients with End-Stage Renal Disease During COVID-19 Pandemic’s Early Months Most US Nursing Homes Had Multiple, Sustained COVID-19 Outbreaks, GAO Reports Association of Childcare Facility Closures With Employment Status of US Women vs Men During the COVID-19 Pandemic US Trends in COVID-19–Associated Hospitalization and Mortality Rates Before and After Reopening Economies Lessons Emerging From COVID-19 Responses by US States

Lung transplantation has become an option of last resort for a small subset of patients with COVID-19-related acute respiratory distress syndrome (ARDS) or pulmonary fibrosis. Ankit Bharat, MD, chief of Thoracic Surgery and director of Lung Transplant and ECMO at Northwestern Memorial Hospital in Chicago, discusses his experience performing lung transplants for patients with respiratory failure due to COVID-19, including the first successful double lung transplant in the US for a patient with COVID-19-related ARDS. Related Content: Lung Transplants for COVID-19—The Option of Last Resort

Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants; An Inside Look at a Post–COVID-19 Clinic; COVID-19 and the “Lost Year” for Smokers Trying to Quit Related Content: Researchers Tie Severe Immunosuppression to Chronic COVID-19 and Virus Variants An Inside Look at a Post–COVID-19 Clinic COVID-19 and the “Lost Year” for Smokers Trying to Quit

COVID-19 leaves some people with a troubling constellation of symptoms that has been known as long-haul COVID but now has a more formal name: postacute sequelae of SARS-CoV-2 infection (PASC). Currently, 33 states in the US have at least 1 clinic dedicated to caring for patients with PASC. Aluko Hope, MD, a pulmonary and critical care physician, cofounded the Montefiore-Einstein COVID-19 Recovery Clinic in New York in 2020. Now the medical director of the Long Covid-19 Program at the Oregon Health & Sciences University, Dr Hope provides insight into the care provided at a post-COVID-19 clinic. Related Content: An Inside Look at a Post–COVID-19 Clinic

Noninvasive ventilation (NIV) may help COVID-19 patients in respiratory failure avoid invasive mechanical ventilation but may also lead to delays in intubation with potential for worse clinical outcomes. Domenico L. Grieco, MD, of Fondazione Policlinico Agostino Gemelli IRCCS in Rome, Jesse B. Hall, MD, of the University of Chicago, and Laveena Munshi, MD, MSc, of Sinai Health System/University Health Network of the University of Toronto join JAMA's live Q&A series to discuss helmet NIV, high-flow nasal oxygen, and other NIV modalities in the management of hypoxic coronavirus patients. Recorded March 25, 2021. Related Content: Effect of Helmet Noninvasive Ventilation vs High-Flow Nasal Oxygen on Days Free of Respiratory Support in Patients With COVID-19 and Moderate to Severe Hypoxemic Respiratory Failure Respiratory Support During the COVID-19 Pandemic: Is It Time to Consider Using a Helmet? Noninvasive Ventilation of COVID-19 Patients

The Price of Success—How to Evaluate COVID-19 Vaccines When They’re Available Outside of Clinical Trials; When the Human Voice Speaks Volumes About Lung Function; COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough Related Articles: The Price of Success—How to Evaluate COVID-19 Vaccines When They’re Available Outside of Clinical Trials When the Human Voice Speaks Volumes About Lung Function COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough

Coronavirus trends, variants, vaccines, treatment, and more. JAMA Associate Editor Preeti Malani, MD, MSJ, also from the University of Michigan, and Emory University School of Medicine's Carlos del Rio, MD, return to JAMA's Q&A series to discuss the latest in COVID-19 medicine and public health. Recorded March 15, 2021. Related Content: COVID-19 in 2021—Continuing Uncertainty Coronavirus Update With Carlos del Rio and Preeti Malani Frequently Asked COVID Vaccine Questions

Genetic variants of the SARS-CoV-2 virus are emerging but so far do not seem to have caused breakthrough infections in people with previous infection or in those who have been vaccinated. John P. Moore, PhD, of Weill Medical College of Cornell University in New York, joins JAMA's Q&A series for an update on the latest variants and what you need to know. Recorded March 4, 2021. Related Article: Approaches for Optimal Use of Different COVID-19 Vaccines

Interview with Christopher J.L. Murray, MD, DPhil, author of The Potential Future of the COVID-19 Pandemic: Will SARS-CoV-2 Become a Recurrent Seasonal Infection? Related Article(s): The Potential Future of the COVID-19 Pandemic

Nancy E. Messonnier, MD is director of the National Center for Immunization and Respiratory Diseases (NCIRD) at the Centers for Disease Control and Prevention (CDC) and leads the CDC’s efforts on COVID-19 vaccination. She joins JAMA's Q&A series to discuss the agency's response to emerging coronavirus variants, the FDA advisory hearings on the new Johnson & Johnson vaccine, and other agency activities and priorities related to COVID-19 control. Recorded February 26, 2021. Related Content: Genetic Variants of SARS-CoV-2—What Do They Mean? Coronavirus Vaccine Update From the CDC With Nancy E. Messonnier, MD SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants Experts Discuss COVID-19—Vaccine Doses, Virus Variants, and More Emergence of a Novel SARS-CoV-2 Variant in Southern California SARS-CoV-2 Variants of Concern in the United States Pregnant People Getting Mixed Messages About COVID-19 Vaccines The Johnson & Johnson Vaccine for COVID-19 SARS-CoV-2 Viral Variants—Tackling a Moving Target Vaccine Distribution—Equity Left Behind? Taking Vaccine to Where the Virus Is—Equity and Effectiveness in Coronavirus Vaccinations?

Interview with James C. Robinson, PhD, author of Funding of Pharmaceutical Innovation During and After the COVID-19 Pandemic

The Pfizer-BioNTech and Moderna COVID-19 mRNA vaccines are the first of many being tested for widespread use. Buddy Creech, MD, MPH, director of the Vanderbilt Vaccine Research Program, reviews these and other vaccines likely to become available, including products that use inactivated, protein subunit, and viral vector immunization strategies. Related Article(s): SARS-CoV-2 Vaccines

The CDC coordinated a massive effort to immunize nearly all nursing home and long-term care facility residents in the US against COVID-19 infection in the month after vaccine approval. Ruth Link-Gelles, PhD, MPH, CDC staff epidemiologist and Lieutenant Commander of the US Public Health Service Commissioned Corps, describes how. Related Article(s): First-Dose COVID-19 Vaccination Coverage Among Skilled Nursing Facility Residents and Staff Nursing Homes’ Next Test—Vaccinating Workers Against COVID-19

Researchers Investigate What COVID-19 Does to the Heart; “Important Conversations” Are Needed to Explain the Nocebo Effect; Therapists Donate Their Time to Counsel Distressed Health Care Workers Related Article: Researchers Investigate What COVID-19 Does to the Heart “Important Conversations” Are Needed to Explain the Nocebo Effect Therapists Donate Their Time to Counsel Distressed Health Care Workers

CDC Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss the agency's response to emerging SARS-CoV-2 variants, implications for the planned vaccine mobilization strategy, the upcoming Johnson & Johnson vaccine FDA advisory hearings, strategies for reopening K-12 schools, and other agency activities and priorities related to COVID-19 control. Recorded February 17, 2021. Related Article(s): Coronavirus Update With CDC Director Rochelle Walensky - February 17, 2021 SARS-CoV-2 Variants of Concern in the United States—Challenges and Opportunities SARS-CoV-2 Viral Variants—Tackling a Moving Target

Paul A. Offit, MD, of The Children's Hospital of Philadelphia returns to JAMA's Q&A series to provide an update on the emergence of COVID-19 variants and their implications for vaccine development, including the Johnson & Johnson vaccine, scheduled for a US Food and Drug Administration VRBPAC hearing on February 26, 2021. Recorded February 11, 2021. Related Article: SARS-CoV-2 Vaccines and the Growing Threat of Viral Variants

Natural experiments comparing coronavirus spread on ships and in hair salons with vs without face masks point to the importance of wearing masks for curbing SARS-CoV-2 spread. John T. Brooks, MD, chief medical officer of the CDC’s COVID-19 response team, reviews recently published epidemiologic data that reinforce the role of mask use for pandemic control. Related Article: Effectiveness of Mask Wearing to Control Community Spread of SARS-CoV-2

As US vaccine distribution expands to include younger healthier populations, questions about vaccine safety in women of childbearing age have become more urgent. University of Texas Southwestern Medical Center's Catherine Y. Spong, MD, and Emory University School of Medicine's Denise J. Jamieson, MD, MPH, both eminent obstetrician/gynecologists, join JAMA's Q&A series to discuss the safety of the Pfizer-BioNTech and Moderna vaccines in pregnant and nursing mothers, and in individuals trying to get pregnant. Recorded February 8, 2021. Related Articles: Pregnancy, Postpartum Care, and COVID-19 Vaccination in 2021 COVID-19 Vaccination in Pregnant and Lactating Women Involving Pregnant Individuals in Clinical Research on COVID-19 Vaccines

Interview with Lawrence O. Gostin, JD, author of Mandating COVID-19 Vaccines

2021 has brought news of emerging SARS-CoV-2 genetic variants that increase transmissibility. Will they diminish vaccine efficacy and lead us to lose pandemic control? University of Michigan's Adam Lauring, MD, PhD, a molecular virologist who uses evolutionary theory to study viral transmission and pathogenesis, joins JAMA's Q&A series to explain the variants and what they mean for public health. Recorded February 4, 2021. Related Article(s): Genetic Variants of SARS-CoV-2—What Do They Mean?

NIAID Director Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss Shifts in the US pandemic response under the Biden administration Emerging genetic variants and implications for vaccine efficacy Prospects for new vaccine approvals and more. Related Article: Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

Interview with Kristin M. Holland, PhD, MPH, author of Trends in US Emergency Department Visits for Mental Health, Overdose, and Violence Outcomes Before and During the COVID-19 Pandemic

Peter Piot, MD, PhD, director of The London School of Hygiene and Tropical Medicine, is a legend in global health, having been involved in identification of HIV and Ebola virus in Africa. He was founding executive director of UNAIDS and Under Secretary-General of the United Nations from 1995 to 2008. He joins JAMA's Q&A series to discuss the global public health response to COVID-19 past, present, and future. Recorded January 28, 2021. Related Article(s): The Challenges Ahead With Monoclonal Antibodies

Interview with Donald C. Goff, MD, author of Association of Psychiatric Disorders With Mortality Among Patients With COVID-19

Ethnic and racial minorities have been particularly hard hit with COVID-19 in some communities. Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses this problem and what has been learned from COVID-19 that can help resolve the general problem of health care disparities. Related Article: Racial and Ethnic Health Disparities Related to COVID-19

To get more vaccine to more people more efficiently, UCSF School of Medicine's Robert M. Wachter, MD, recently urged giving a single dose now and deferring the second dose until more vaccine is available. Paul A. Offit, MD, of The Children's Hospital of Philadelphia, disagrees. The two discuss the pros and the cons of the plan and alternative responses to road bumps in the US vaccine rollout, on JAMA's live Q&A series. Recorded January 19, 2021. Related Article: Developing a SARS-CoV-2 Vaccine at Warp Speed

Incoming Centers for Disease Control and Prevention (CDC) Director Rochelle P. Walensky, MD, MPH, returns to JAMA's Q&A series to discuss her vision and priorities for the agency and changes in its pandemic response strategies, when she takes the reins on January 20. Recorded January 19, 2021. Related Article(s): All-Cause Excess Mortality and COVID-19–Related Mortality Among US Adults Aged 25-44 Years, March-July 2020

Editor in Chief Fred Rivara and Deputy Editor Steve Fihn discuss research published in JAMA Network Open in January 2021 Related Article: Association of Intensive Care Unit Patient Load and Demand With Mortality Rates in US Department of Veterans Affairs Hospitals During the COVID-19 Pandemic SARS-CoV-2 Transmission From People Without COVID-19 Symptoms Intensive Care Unit Strain and Mortality Risk Among Critically Ill Patients With COVID-19—There Is No “Me” in COVID

Mitchell Katz, MD, president and chief executive officer of New York City Health + Hospitals, and former Los Angeles County health agency director, discusses causes, similarities, and differences between the spike of COVID-19 cases, hospitalizations, and deaths in the 2 cities. Related Article: Modernize Medical Licensing, and Credentialing, Too—Lessons From the COVID-19 Pandemic

The COVID-19 pandemic has prompted scientists to use adaptive research designs to evaluate potential treatments simultaneously and efficiently, increasing the likelihood that patients will receive treatments most likely to be effective for them. Lennie Derde, MD, of University Medical Center Utrecht in the Netherlands and JAMA Associate Editor Christopher W. Seymour, MD, of University of Pittsburgh Medical Center join JAMA's Q&A series to discuss the latest in critical care management of COVID-19 patients and emerging treatment strategies and therapies. Recorded January 13, 2021. Related Article(s): Sensible Medicine-Optimizing the Trade-off Between Learning and Doing in a Pandemic

Arnold S. Monto, MD, chaired the US Food and Drug Administration's Vaccines and Related Biological Products Advisory Committee (VRBPAC) meetings in December that led to Emergency Use Authorization (EUA) of the Pfizer/BioNTech and Moderna vaccines. He joins JAMA's Q&A series from the University of Michigan School of Public Health to discuss experience to date with the 2 products and what's next in vaccine development. Recorded January 11, 2021. Related Article(s): Experts Discuss COVID-19: Vaccine Allocation, Placebo Groups, and More

Interview with Samyukta Mullangi, MD, MBA, author of The COVID-19 Pandemic—An Opportune Time to Update Medical Licensing; also with Mitchell H. Katz, MD, chief executive officer of New York City Health and Hospitals and author of Modernize Medical Licensing, and Credentialing, Too—Lessons From the COVID-19 Pandemic

Aaloke Mody, MD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study that uses Lorenz curves as a metric for quantifying racial inequities in coronavirus disease 2019 (COVID-19) testing. Read the article here: https://ja.ma/2MOMjWG. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Gregory Armstrong, MD, director of the Advanced Molecular Detection Program for the CDC, explains what is currently known about the new mutations of SARS-CoV-2. Related Article(s): Genetic Variants of SARS-CoV-2—What Do They Mean?

Tom Shimabukuro, MD, MPH, MBA, and Sara Mbaeyi, MD, MPH, from the CDC discuss rare allergic complications in patients who received the first dose of the Pfizer-BioNTech vaccine between December 14-23, 2020.

Adam Lauring, MD, PhD, from the University of Michigan Division of Infectious Diseases, an expert on the evolutionary biology of RNA viruses, explains the new genetic variants recently found in SARS-CoV-2 and their importance. Related Article(s): Genetic Variants of SARS-CoV-2—What Do They Mean?

Nicole Kravitz-Wirtz, PhD, MPH, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study describing individuals’ concerns regarding violence in the context of the coronavirus disease 2019 (COVID-19) pandemic, experiences of pandemic-related unfair treatment, prevalence of and reasons for firearm acquisition, and changes in firearm storage practices due to the pandemic. Read the article here: https://ja.ma/2X7lC1x. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Elderly persons and residents of nursing homes have been the hardest hit in the COVID-19 pandemic. Harvard geriatrician Sharon Inouye, MD, discusses the effect COVID-19 has had on nursing homes and what should be done about it. Related Article: Association of Nursing Home Ratings on Health Inspections, Quality of Care, and Nurse Staffing With COVID-19 Cases

Communication science expert Brian Southwell, PhD, recently launched a training workshop at the Duke University School of Medicine to address a major clinical problem: What should physicians do when patients are misinformed about their health? It’s one of only a few such programs in the nation. Southwell, a scholar with the medical school’s Social Science Research Institute and a senior director at the independent, nonprofit research institute RTI International, chatted with JAMA Medical News Associate Managing Editor Jennifer Abbasi about the viral spread of false health information and malicious disinformation campaigns, why we’re vulnerable to falling for them, and how time-pressed physicians can deal with all the noise. Related Article(s): COVID-19 Conspiracies and Beyond: How Physicians Can Deal With Patients’ Misinformation

Emily A. Largent, JD, PhD, RN, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study assessing the acceptability of coronavirus disease 2019 (COVID-19) vaccine mandates among members of the US public. Read the article here: https://ja.ma/3nGKAQP. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

With coronavirus vaccines now available, what are the timeline and prospects for "herd immunity" and return to a new normal? Marc Lipsitch, DPhil, of Harvard T.H. Chan School of Public Health returns to JAMA's Q&A series with Paul D. Biddinger, MD, director of Massachusetts General Hospital's Center for Disaster Medicine, to discuss. Recorded December 17, 2020. Related Article: The Ethics of Continuing Placebo in SARS-CoV-2 Vaccine Trials

Ala Stanford, MD, founder of Philadelphia’s Black Doctors COVID-19 Consortium, talks with JAMA Medical News Staff Writer Mary Chris Jaklevic about her work to establish COVID-19 testing sites for the city’s Black residents. Related Article: Surgeon Fills COVID-19 Testing Gap in Philadelphia’s Black Neighborhoods

Peter W. Marks, MD, PhD, and Stephen M. Hahn, MD, return to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the data, the weekend's EUA designation (Pfizer/BioNTech), and the process for future full licensure and postmarketing safety surveillance. Dr Marks directs the US FDA's Center for Biologics Evaluation and Research (CBER). Dr Hahn is commissioner of the US Food and Drug Administration. Recorded December 14, 2020. Related Article(s): Behaviorally Informed Strategies for a National COVID-19 Vaccine Promotion Program

Hannah Wunsch, MD, MSc, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study comparing the New York State Ventilator Allocation Guideline with the original triage criteria proposed by White and Lo to determine which and how many admissions to US intensive care units are identified as having the lowest priority for ventilator allocation. Read the article here: https://ja.ma/37k0sTE. Watch the JAMA Coronavirus Q&A with Douglas B. White, MD, MAS from March 27, 2020: https://edhub.ama-assn.org/jn-learning/video-player/18365657 JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

JAMA Fishbein Fellow Kristin Walter, MD, interviews Craig Garfield, MD, and Richard Weissbourd, EdD, about parental relationships during the COVID-19 pandemic. Related Article: Considerations for Young Children and Those With Special Needs as COVID-19 Continues

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the Pfizer/BioNTech and Moderna vaccines: the public data, deliberations at Thursday's FDA Advisory Committee meeting, and prospects for an agency Emergency Use Authorization designation, licensure, and rollout. Recorded December 11, 2020. Related Article(s): Coronavirus Infections—More Than Just the Common Cold

The COVID Tracking Project, launched by The Atlantic, collects and publishes data required to understand the COVID-19 outbreak in the US, including data on race and ethnicity needed to understand health inequities in the outbreak. Atlantic Monthly journalists Alexis C. Madrigal and Erin Kissane join JAMA's Q&A series to describe the project and their experience developing a database for fact-based health reporting on the pandemic. Recorded December 10, 2020.

Lockdowns resulting from COVID-19 have had a devastating effect on everyone’s personal lives and the economy. What factors in people’s daily lives are most associated with SARS-CoV-2 transmission between people? Manish Patel, MD, team lead of the CDC’s Influenza Prevention & Control Team, discusses a study they conducted examining what sorts of activities might be associated with COVID-19 disease transmission. Related Article(s): Community Outbreak Investigation of SARS-CoV-2 Transmission Among Bus Riders in Eastern China

Ellen H. Lee, MD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study describing the distribution of race/ethnicity among cases of coronavirus disease 2019 (COVID-19)–associated multisystem inflammatory syndrome in children reported to the New York City Department of Health and Mental Hygiene. Read the article here: https://ja.ma/37vCJ1K. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Closing businesses during the COVID-19 pandemic has had devastating consequences for individuals and the economy in general. Proper air handling combined with the use of masks and physical distancing can greatly improve the safety of indoor spaces. Joseph Allen, DSc, MPH, assistant professor of exposure assessment science at Harvard T.H. Chan School of Public Health, and Andrew Ibrahim, MD, assistant professor of surgery and architecture and urban planning at the University of Michigan, discuss air conditioning standards that can substantially reduce the risk of disease transmission in indoor spaces. Related Article(s): Turbulent Gas Clouds and Respiratory Pathogen Emissions

With the Pfizer and Moderna coronavirus vaccines reportedly under review at the US FDA for Emergency Use Authorization (EUA), Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on what to expect, prospects for vaccine rollout and distribution in the coming months, and ongoing safety surveillance. Recorded December 2, 2020. Related Article: Developing a SARS-CoV-2 Vaccine at Warp Speed

Yale Sterling Professor Nicholas A. Christakis, MD, PhD, returns to JAMA's Q&A series to discuss the surge in US cases and other recent pandemic developments. Dr Christakis is author of the recently published book "Apollo's Arrow: The Profound and Enduring Impact of Coronavirus on the Way We Live." Recorded November 23, 2020.

Maura Kennedy, MD, MPH, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study examining how frequently older adults with coronavirus disease 2019 (COVID-19) present to the emergency department with delirium and their associated hospital outcomes. Read the article here: https://ja.ma/3q5h74S. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

In the midst of rising COVID-19 case rates globally, Derek C. Angus, MD, MPH, and Rochelle P. Walensky, MD, MPH, return to JAMA's Q&A series to update viewers on developments in the pandemic and the critical care management of COVID-19 patients. Dr Angus is Chief Health Care Innovation Officer at the University of Pittsburgh Medical Center, professor and chair of Critical Care Medicine, and a senior JAMA editor. Dr Walensky is Chief of Infectious Diseases at Massachusetts General Hospital and a professor at Harvard Medical School. Recorded November 19, 2020. Related Article(s): Optimizing the Trade-off Between Learning and Doing in a Pandemic

Interview with Ipsit V. Vahia, MD, author of Older Adults and the Mental Health Effects of COVID-19 Related Article(s): Older Adults and the Mental Health Effects of COVID-19

Would letting coronavirus infect the broad US and global population be a safe and effective means of ending the COVID-19 pandemic? Jay Bhattacharya, MD, PhD, of Stanford University's Center for Primary Care and Outcomes Research is a signatory of the "Great Barrington Declaration," which proposes to "allow those at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk." Marc Lipsitch, PhD, of the Harvard T.H. Chan School of Public Health, a signatory of the "John Snow Memorandum," which refutes the argument, responds. Related Article: Herd Immunity and Implications for SARS-CoV-2 Control

Ngozi O. Ezike, MD, director of the Illinois Department of Public Health, discusses state and regional management of the COVID-19 pandemic. Recorded November 9, 2020. Related Article(s): Universal Masking in the United States

Catherine R. Butler, MD, MA joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a qualitative study describing the perspectives and experiences of clinicians involved in institutional planning for resource limitation and/or patient care during the coronavirus disease 2019 (COVID-19) pandemic. Read the article here: https://ja.ma/32vBC0h. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Roy H. Perlis, MD, MSc, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study assessing admission laboratory and comorbidity features associated with critical illness and mortality risk among patients hospitalized with coronavirus disease 2019 (COVID-19) across 6 Eastern Massachusetts hospitals. Read the article here: https://ja.ma/384dBkt. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Carlos del Rio, MD, author of Long-term Health Consequences of COVID-19 Related Article: Long-term Health Consequences of COVID-19

JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the November 2, 2020 issue.

Tim Uyeki, MD, chief medical officer for the Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), discusses how the COVID-19 pandemic may affect the 2020-2021 influenza season. Related Article: Preparing for the 2020-2021 Influenza Season

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic, including the continued importance of nonpharmaceutical interventions (masking, handwashing, physical distancing) for managing rising case numbers in the US and globally. Recorded October 28, 2020. Related Article(s): Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

Paul A. Offit, MD, of the Children's Hospital of Philadelphia, returns to JAMA's Q&A series to provide an update on progress in COVID-19 vaccine development. Recorded October 27, 2020. Related Article(s): Developing a SARS-CoV-2 Vaccine at Warp Speed

John S. Brownstein, PhD and Douglas L. Kriner, PhD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study evaluating the factors associated with US adults’ choice of and willingness to accept a hypothetical COVID-19 vaccine. Read the article here: https://ja.ma/3e0Rz3i. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Large Meta-analysis Digs Into Obesity’s COVID-19 Risks; As Their Numbers Grow, COVID-19 “Long Haulers” Stump Experts; Telephone Visits Surge During the Pandemic, but Will They Last? Related articles: Large Meta-analysis Digs Into Obesity’s COVID-19 Risks As Their Numbers Grow, COVID-19 “Long Haulers” Stump Experts Telephone Visits Surge During the Pandemic, but Will They Last?

Interview with Aaron L. Baggish, MD, and Jonathan H Kim, MD, authors of Coronavirus Disease 2019 and the Athletic Heart: Emerging Perspectives on Pathology, Risks, and Return to Play, and James E. Udelson, MD, author of Return to Play for Athletes After Coronavirus Disease 2019 Infection—Making High-Stakes Recommendations as Data Evolve

Rochelle P. Walensky, MD, MPH, of Harvard Medical School and Massachusetts General Hospital returns to JAMA's COVID-19 Q&A to provide an update on developments in the pandemic. She is a signatory of the recent John Snow Memorandum emphasizing the importance of public health interventions to manage the spread of COVID-19. Recorded October 22, 2020. Related Article(s): Preventing the Spread of SARS-CoV-2 With Masks and Other “Low-tech” Interventions

The costs of the coronavirus pandemic are unprecedented in their dimensions: David M. Cutler, PhD, of Harvard University discusses financial costs: the $16 trillion virus. Lisa Cooper, MD, MPH, of Johns Hopkins University discusses the costs to communities of color in excess deaths and bereavement. Charles R. Marmar, MD, of NYU Grossman School of Medicine discusses the mental health costs. Recorded October 20, 2020. Related Article(s): The COVID-19 Pandemic and the $16 Trillion Virus

Andy Slavitt, MBA, discusses recent developments in the COVID-19 pandemic and the US response. Slavitt is former Acting CMS Administrator in the Obama administration, board director at the United States of Care in Washington, DC, and a Distinguished Health Policy Fellow at the Leonard Davis Institute of Health Economics at the University of Pennsylvania in Philadelphia. Recorded October 16, 2020. Related Article: The COVID-19 Pandemic Underscores the Need to Address Structural Challenges of the US Health Care System

Many people are hoping that enough people develop resistance to COVID-19, either from being exposed to the disease or from vaccination, to develop herd immunity that will enable society to return to normal. But will that happen? Saad Omer, MD, from the Yale Institute for Global Health, discusses his JAMA article on herd immunity and how much we can count on having it to return society to normal from this COVID-19 pandemic. Related Article(s): Herd Immunity and Implications for SARS-CoV-2 Control

The National Academy of Medicine has recommended that racial minority populations receive priority for vaccination because they have been hard hit by the pandemic and are "worse off" socioeconomically. US law is inconsistent on whether race/ethnicity can be an explicit criterion for achieving equity and diversity. Lawrence O. Gostin, JD, of Georgetown University and Michelle A. Williams, ScD, of Harvard T.H. Chan School of Public Health discuss ways to achieve the public health objective of protecting vulnerable communities while adhering to law and ethics. Recorded October 14, 2020. Related Article(s): Is It Lawful and Ethical to Prioritize Racial Minorities for COVID-19 Vaccines?

Interview with Christopher W. Seymour, MD, MSc, author of Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic Related Article(s): Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic

University of North Carolina (UNC) at Chapel Hill nutrition scholar Barry Popkin, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss new findings on obesity and COVID-19. Popkin is the lead author of a systematic review and meta-analysis on the topic that was published recently in Obesity Reviews. He is a distinguished professor in the department of nutrition at the UNC Gillings School of Global Public Health. Related Article(s): Large Meta-analysis Digs Into Obesity’s COVID-19 Risks

On October 2 the US National Academies of Science, Engineering, and Medicine issued its consensus Framework for Equitable Allocation of a COVID-19 Vaccine. William H. Foege, MD, MPH, emeritus distinguished professor of International Health at the Rollins School of Public Health at Emory University, cochaired the committee that authored the report and discusses its recommendations. Recorded October 2, 2020. Related Article: Fairly Prioritizing Groups for Access to COVID-19 Vaccines

Peter Marks, MD, PhD, directs the US FDA's Center for Biologics Evaluation and Research (CBER) and will "call the balls and strikes" on any COVID-19 vaccine, according to FDA Commissioner Stephen Hahn. He joins JAMA Editor Howard Bauchner, MD, for an update on vaccine progress to date and prospects for pre-election political interference in the FDA approval process. Recorded October 5, 2020. Related Article(s): Unwavering Regulatory Safeguards for COVID-19 Vaccines

Sarah E. Gollust, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a survey study examining public perception of high priority groups for receipt of an eventual coronavirus disease 2019 vaccine in case of shortage of supply. Read the article here: https://ja.ma/3d2101T. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Sweden’s response to the COVID-19 pandemic differed from its neighbors in Europe. Lockdowns were minimized with the belief that they would be more damaging than the virus itself. Much criticism was levied at the country regarding these policies. Anders Tegnell, MD, is the head of the Department of Public Health Analysis and Data Management, Deputy Director General at the Public Health Agency of Sweden, and had been Sweden's state epidemiologist since 2013. He discusses what Sweden did in response to COVID-19 and what their outcomes were. Related Article: COVID-19 and Health Equity—A New Kind of “Herd Immunity”

H. Nina Kim, MD, MSc and Herbert C. Duber, MD, MPH join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study evaluating the proportion of patients tested for coronavirus disease 2019 (COVID-19) and the proportion of positive cases, using language as a surrogate for immigrant status. Read the article here: https://ja.ma/3d2101T. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Anthony S. Fauci, MD, returns to JAMA's Q&A series to discuss the latest developments in the COVID-19 pandemic. Recorded September 25, 2020. Related Article(s): Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine

Michael T. Osterholm, PhD, MPH, returns to JAMA's Coronavirus Q&A series to discuss the latest developments in the COVID-19 pandemic. He is director of the Center for Infectious Disease Research and Policy (CIDRAP) at University of Minnesota and a veteran of pandemic planning. Recorded September 23, 2020. Related Article(s): Fairly Prioritizing Groups for Access to COVID-19 Vaccines

Hydroxychloroquine and convalescent plasma approvals by the FDA under Emergency Use Authorization (EUA) protocols have raised concerns the agency is under withering political pressure to fast-track a COVID-19 vaccine before it is proven safe and effective. Joshua Sharfstein, MD, Johns Hopkins Bloomberg School of Public Health, and JAMA Associate Editor Preeti Malani, MD, University of Michigan, discuss implications for public health and policy responses to ensure vaccine safety. Recorded September 18, 2020. Related Article: Reassuring the Public and Clinical Community About the Scientific Review and Approval of a COVID-19 Vaccine

What Happens When COVID-19 Collides With Flu Season?; Flu Vaccination Urged During COVID-19 Pandemic; COVID-19 and mRNA Vaccines—First Large Test for a New Approach Related Article(s): What Happens When COVID-19 Collides With Flu Season? Flu Vaccination Urged During COVID-19 Pandemic COVID-19 and mRNA Vaccines—First Large Test for a New Approach

Science communications expert Dominique Brossard, PhD, and JAMA Medical News Associate Managing Editor Jennifer Abbasi discuss research-based strategies to encourage mask wearing, social distancing, and hand washing during the COVID-19 pandemic. Dr. Brossard is a professor and chair of the Department of Life Sciences Communication at the University of Wisconsin-Madison and part of a new COVID-19-focused National Academies of Science, Engineering, and Medicine group. Related Article(s): The Science of Persuasion Offers Lessons for COVID-19 Prevention

Song Gao, PhD and Ajay K. Sethi, PhD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study using anonymous location data from 45 million mobile phones to determine if stay-at home orders were associated with decreased median travel distance and slower #COVID19 spread. Read the article here: https://ja.ma/2ZCqm0A. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Aaron S. Kesselheim, MD, author of Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency Related Article(s): Regulatory Decision-making on COVID-19 Vaccines During a Public Health Emergency

New data show unfavorable US trends in hypertension and obesity, with communities of color doing worse. National Institute of Diabetes and Digestive and Kidney Diseases Director Griffin P. Rodgers, MD, and National Heart, Lung, and Blood Institute Director Gary H. Gibbons, MD, discuss the implications for COVID-19 outcomes and public health. Recorded September 10, 2020. Related Article(s): Trends in Blood Pressure Control Among US Adults With Hypertension, 1999-2000 to 2017-2018

JAMA Pediatrics Editors' Summary by Dimitri Christakis, MD, MPH, Editor in Chief, and Frederick Rivara, MD, MPH, Editor in Chief of JAMA Network Open for the September 8, 2020 issue.

David O. Meltzer, MD, PhD, joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study examining whether patients’ most recent vitamin D levels and treatment for insufficient vitamin D levels are associated with test results for coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/2ZkvGpf. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

A conversation with Jonathan A. C. Sterne, MA, MSc, PhD, of the University of Bristol, Todd W. Rice, MD, MSc, of Vanderbilt University, and Janet V. Diaz, MD, of the World Health Organization (WHO) on the latest research supporting the use of hydrocortisone and dexamethasone for treatment of COVID-19 ARDS. Recorded September 2, 2020. Related Article(s): Effect of Hydrocortisone on 21-Day Mortality or Respiratory Support Among Critically Ill Patients With COVID-19

COVID-19 continues to rapidly spread throughout the world. In the past few months, the population affected by the disease has shifted from older to younger patients. Public health officials are concerned that younger people seem not to be very compliant with recommendations regarding masking and social distancing. It is believed that younger people think that the adverse consequences of the disease occur in the elderly and not in them. Garret Salzman, MD, is a resident physician at UCLA and contracted the disease. He is young and healthy, but he has had substantial disability from COVID-19. He tells a cautionary tale of his experience with COVID-19 that this is not a benign disease in young people, that they need to be careful. Related Article: Potential Implications of COVID-19 for the 2020-2021 Residency Application Cycle

Paul A. Offit, MD, of the Children's Hospital of Philadelphia provides an update on COVID-19 vaccine development. Recorded August 24, 2020. Related Article: Developing a SARS-CoV-2 Vaccine at Warp Speed

Alyssa Bilinski, MS, and Joshua A. Salomon, PhD, join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a mathematical modeling study examining the potential for contract tracing to reduce the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the context of reduced physical distancing under different assumptions for case detection, tracing, and quarantine efficacy. Read the article here: https://ja.ma/3ixDJ9j JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

CDC Director Robert Redfield, MD, discusses recent developments in the COVID-19 pandemic and US response, including prospects for dual outbreaks of COVID-19 and influenza in the fall and winter. Related Article(s): Addressing Influenza Vaccination Disparities During the COVID-19 Pandemic

Ezekiel Emanuel, MD, PhD, of the University of Pennsylvania's Perelman School of Medicine, Department of Medical Ethics and Health Policy, discusses recent developments in the COVID-19 pandemic. Recorded August 19, 2020. Related Article(s): The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

As the COVID-19 pandemic continues to spread throughout the world, flu season is almost upon us. This is concerning because there will be an overlap between flu and COVID-19 and patients could get both diseases. Daniel Solomon, MD, from the Division of Infectious Diseases at the Brigham and Women’s Hospital of the Harvard Medical School in Boston, discusses COVID-19 and how the flu might pan out this year. Related Article: Influenza in the COVID-19 Era

Before COVID-19, even though most children got vaccinated for measles, too many did not, resulting in worsening outbreaks of measles. People forgot how bad a disease measles is and became lax about getting their children vaccinated. Now in the COVID-19 era everyone is aware of what an out-of-control infectious disease can do and we are all anxiously awaiting a COVID-19 vaccine. Will this experience help encourage parents to get their children vaccinated? We discussed the problems of an adequate measles vaccination with Dr. Saad Omer, PhD, from the Yale Institute for Global Health at Yale University in New Haven, Connecticut. Related Article(s): Vaccine Refusal and Measles Outbreaks in the US

One of the most contentious issues relating to COVID-19 is when to reopen schools. This is a complicated matter because placing people in close quarters risks spread of the disease. Yet children being at home makes it difficult for their working parents to manage their affairs and can potentially affect the learning experience. JAMA Associate Editor Preeti Malani, MD, chief health officer for the University of Michigan, discusses school reopening and how the University of Michigan is addressing this problem. Related Article: Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

The use of hydroxychloroquine as a treatment for COVID-19 serves as an example of what is wrong with medical information being widely disseminated before it is thoroughly vetted by peer review. Preliminary studies of this treatment modality were spread widely, creating false hope that a treatment for COVID-19 existed. Several randomized trials have shown that hydroxychloroquine is not an effective therapy for COVID-19. David Juurlink, MD, PhD, from the University of Toronto summarizes the evidence base regarding hydroxychloroquine and COVID-19. Related Article(s): Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)

Harvey W. Kaufman, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining changes in the number of patients with newly identified cancer before and during the coronavirus disease 2019 (COVID-19) pandemic in the United States. Read the article here: https://ja.ma/31khw7X. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Soumya Swaminathan, MD, DNB, chief scientist at the World Health Organization (WHO), discusses the global coronavirus pandemic and the WHO response. Recorded August 5, 2020. Related Article: COVID-19 Reveals Urgent Need to Strengthen the World Health Organization

Anthony Fauci, MD, White House Coronavirus Task Force member and director of the National Institute of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded August 3, 2020. Related Article(s): Anthony Fauci, MD, on COVID-19 Vaccines, Larry Kramer, and Dealing With Criticism

Few treatments have proven to be effective for treating COVID-19. Recently, a clinical trial reporting the results of dexamethasone for treating COVID-19 was published and has received a great deal of attention in the popular media. Greg Curfman, MD, JAMA Deputy Editor, reviews the study and discusses what the findings do or do not reveal about the efficacy of dexamethasone for treating COVID-19. Related Article(s): Missed Opportunities on Emergency Remdesivir Use

Interview with Madeline R. Sterling, MD, author of Experiences of Home Health Care Workers in New York City During the Coronavirus Disease 2019 Pandemic: A Qualitative Analysis, and Theresa A. Allison, MD, PhD, author of Extreme Vulnerability of Home Care Workers During the COVID-19 Pandemic—A Call to Action

Roberta L. Schwartz, PhD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cross-sectional study examining rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among asymptomatic health care workers and community residents in the greater Houston, Texas, area. Read the article here: https://ja.ma/3f8lvcz. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

US Food and Drug Administration (FDA) Commissioner Stephen Hahn, MD, discusses the agency's role in responding to the COVID-19 pandemic. Recorded July 30, 2020. Related Article: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV)

Katherine Auger, MD, MSc, of Cincinnati Children's Hospital and Julie Donohue, PhD, of University of Pittsburgh's Graduate School of Public Health discuss K-12 school reopening policy options and the way forward for the 2020-21 school year. Recorded July 29, 2020. Related Article(s): Association Between Statewide School Closure and COVID-19 Incidence and Mortality in the US

Ford Foundation President Darren Walker discusses the role of philanthropic organizations in responding to the COVID-19 pandemic and to health inequities. Recorded July 28, 2020. Related Article(s): The Work of Philanthropy in Responding to COVID-19 and Addressing Inequality

David N. Fisman, MD, MPH joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines the trends and risk factors associated with coronavirus disease 2019 (COVID-19) death in long-term care facilities in Ontario, Canada. Read the article here: https://ja.ma/39oLDyy. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Eric Topol, MD, Scripps Research EVP and omnivorous science health care and tech commentator, discusses the evolving COVID-19 pandemic. Recorded July 23, 2020. Related Article: Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers

Catherine L. Auriemma, MD joins JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a cohort study that examines changes in completion of and expressed preferences on an online advanced directive platform during the coronavirus 2019 (COVID-19) pandemic. Read the article here: https://ja.ma/39gbXLe. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Both remdesivir and dexamethasone have been promoted as effective treatments for COVID-19. JAMA Deputy Editor Greg Curfman, MD, and Professor Rachel Sachs, JD, from the Washington University School of Law discuss the science and health policy aspects of these COVID-19 treatments. Related Article(s): Missed Opportunities on Emergency Remdesivir Use

CDC Director Robert R. Redfield, MD, discusses the ongoing COVID-19 pandemic and the agency’s latest recommendations. Recorded July 14, 2020. Related Article(s): Universal Masking to Prevent SARS-CoV-2 Transmission—The Time Is Now

Ramez Kouzy, MD, Joseph Abi Jaoude, MD, and Ethan Ludmir, MD join JAMA Network Open Digital Media Editor, Seth Trueger, MD, MPH, to discuss a systematic review examining current randomized clinical trials of therapeutic agents to treat coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/2B21PJs.  

Kalpalatha K. Guntupalli, MD, of Baylor College of Medicine discusses the surge and ICU management of COVID-19 patients in Houston, Texas. Recorded July 10, 2020. Related Article(s): Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area

Whether the SARS-CoV-2 virus is transmitted by droplets or aerosol influences which public health interventions might slow its spread. Michael Klompas, MD, professor of medicine at Harvard Medical School, explains evidence to date about mechanisms of coronavirus transmission and implications for pandemic containment and mitigation efforts. Related: Airborne Transmission of SARS-CoV-2: Theoretical Considerations and Available Evidence

Infectious disease physician Rochelle P. Walensky, MD, of Harvard University discusses the ongoing COVID-19 pandemic. Recorded July 8, 2020. Related Article: Airborne Spread of SARS-CoV-2 and a Potential Role for Air Disinfection

Anthony Fauci, MD, White House Coronavirus Task Force member and Director of the National Institutes of Allergy and Infectious Diseases, discusses latest developments in the COVID-19 pandemic. Recorded on July 2, 2020.

Interview with Daniel M. Weinberger, PhD, author of Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses latest developments in the COVID-19 pandemic. Recorded on June 29, 2020. Related Article(s): Interpreting Diagnostic Tests for SARS-CoV-2

Alhaji Cherif, PhD and Peter Kotanko, MD join JAMA Network Open Editors to discuss a study examining the feasibility of using pool testing to identify patients with coronavirus disease 2019 (COVID-19) in a setting with limited testing availability. Read the article here: https://ja.ma/3e8OCvJ JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Intensivists Flavia R. Machado, MD, PhD, of the Federal University of São Paulo, and Jorge Salluh, MD, PhD, of the D’OR Institute for Research and Education in Rio de Janeiro, discuss the surge of COVID-19 cases and ICU management of patients in Brazil. Recorded June 26, 2020. Related Article(s): Latin America and Its Global Partners Toil to Procure Medical Supplies as COVID-19 Pushes the Region to Its Limit

Chicago public health legend and retired physician Linda Rae Murray, MD, discusses systemic racism and the pandemic’s disproportionate effect among African Americans and other people of color with JAMA Medical News Associate Managing Editor Jennifer Abbasi. Dr Murray is an adjunct assistant professor at the University of Illinois at Chicago School of Public Health and a past president of the American Public Health Association. Related: Taking a Closer Look at COVID-19, Health Inequities, and Racism  

Michael Osterholm, PhD, MPH, of UMN's Center for Infectious Disease Research and Policy, discusses the summer rise in US COVID-19 cases, prospects for school reopening, a "second wave" in the fall, and more. Recorded June 24, 2020. Related Article(s): Vulnerability to Pandemic Flu Could Be Greater Today Than a Century Ago

Gina M. Piscitello, MD joins JAMA Network Open Editors to discuss a systematic review that examines US state guidelines for ventilator allocation decision-making during the coronavirus disease 2019 pandemic. Read the article here: https://ja.ma/2YpfVxf. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Fabio Ferreli, MD, and Giuseppe Mercante, MD, authors of Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019

Infectious disease and global health expert Carlos del Rio, MD, of Emory University provides an update on the status of the #COVID19 pandemic in summer 2020, prospects for effective treatment and prevention, communicating the ongoing risk to the public, and more. Recorded June 15, 2020. Related Article: Translating Science on COVID-19 to Improve Clinical Care and Support the Public Health Response

COVID-19 critical care update with Maurizio Cecconi, MD, of Humanitas University in Milan, Italy, and JAMA Associate Editor Derek C. Angus, MD, MPH, of the University of Pittsburgh. Recorded June 8, 2020. Related Article: Management of COVID-19 Respiratory Distress

Joseph M. Unger, PhD joins JAMA Network Open Editors to discuss a cohort study investigating how the coronavirus disease 2019 (COVID-19) pandemic is associated with national enrollment in cancer clinical trials. Read the article here: https://ja.ma/2MNv1Gs. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Interview with Jay Shore, MD, MPH, author of Telepsychiatry and the Coronavirus Disease 2019 Pandemic—Current and Future Outcomes of the Rapid Virtualization of Psychiatric Care

Joshua M. Sharfstein, MD, and Christopher Morphew, PhD, of Johns Hopkins University discuss options for opening primary, middle, and high schools in fall 2020. Recorded June 3, 2020. Related Article: The Urgency and Challenge of Opening K-12 Schools in the Fall of 2020

NIAID Director Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor in Chief Howard Bauchner, MD. Recorded June 2, 2020. Related Article(s): Anthony Fauci, MD, on COVID-19 Vaccines, Larry Kramer, and Dealing With Criticism

Paul Offit, MD, of the Children's Hospital of Philadelphia, discusses principles and progress to date in COVID-19 vaccine development. Recorded June 1, 2020. Related: Interview with Brit Trogen, MD, MS, author of Adverse Consequences of Rushing a SARS-CoV-2 Vaccine: Implications for Public Trust

Tristan Morichau-Beauchant, MD joins JAMA Network Open Editors to discuss a case series that reports a systematic assessment of deep vein thrombosis among patients in an intensive care unit in France with severe coronavirus disease 2019 (COVID-19). Read the article here: https://ja.ma/307784k. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Paul Starr, PhD, Professor of Sociology and Public Affairs at Princeton University, discusses policy options for achieving a new normal in the COVID-19 pandemic. Recorded Thursday, May 28, 2020. Related Article: Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic

US National Institutes of Health (NIH) Director Francis S. Collins, MD, PhD, discusses the agency's new initiative to collaborate with other agencies and industry to accelerate development and testing of COVID-19 treatments and vaccines. Recorded May 19, 2020. Related: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV): An Unprecedented Partnership for Unprecedented Times

The University of New Mexico's Eileen Barrett, MD, MPH, speaks with JAMA's Jennifer Abbasi about the pandemic's mental and emotional toll on health care workers—and how they and their employers can safeguard their well-being. Read the article: Prioritizing Physician Mental Health as COVID-19 Marches On

Was the stay-at-home order in Illinois associated with different rates of coronavirus disease 2019 (COVID-19) compared with Iowa, which did not issue a stay-at-home order? Wei Lyu, MS and George L. Wehby, PhD join JAMA Network Open Editors to discuss a cross-sectional study comparing coronavirus disease 2019 (COVID-19) cases in border counties in Iowa and Illinois to find out if issuing a stay-at-home order helped limit the spread of COVID-19 cases. Read the article here: https://ja.ma/2LNprmO. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Ezekiel Emanuel, MD, PhD, of the Perelman School of Medicine's Department of Medical Ethics and Health Policy, discusses the use of immunity licensing (immunity passports) as a means to restore public travel, activity, and the economy following the first wave of the COVID-19 pandemic. Recorded May 11, 2020. Related: The Ethics of COVID-19 Immunity-Based Licenses (“Immunity Passports”)

Ruoran Li, MPhil joins JAMA Network editors to discuss a comparative effectiveness study describing and comparing the intensive care unit and inpatient bed needs for patients with coronavirus disease 2019 (COVID-19) in 2 cities in China to estimate the peak number of intensive care unit beds needed in US cities if an outbreak equivalent to that in Wuhan occurs. Read the article here: https://ja.ma/3cySE0m.   JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Preprint servers and professional discourse on social media sites like Twitter have been incredibly helpful in spreading useful information as the COVID-19 pandemic changes over time. But they clearly function as a double-edged sword, spreading information rapidly prior to traditional peer review. JAMA Network Open Editors Eli Perencevich, MD, MS and Roy Perlis, MD, MSc join us to discuss on JNOLive. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

Don Berwick, MD, MPP, of the Institute for Healthcare Improvement, discusses choices societies and the medical profession can make to improve health care and reduce inequities as we move out of the acute phase of the coronavirus pandemic.

Anne Schuchat, MD, Principal Deputy Director of the Centers for Disease Control and Prevention (CDC), discusses evolution of CDC guidance and latest developments in the COVID-19 pandemic. Recorded Friday May 1, 2020.

Interview with Hsien-Ho Lin, MD, ScD, author of Contact Tracing Assessment of COVID-19 Transmission Dynamics in Taiwan and Risk at Different Exposure Periods Before and After Symptom Onset

The US spends more on health care as a proportion of its GDP than any other nation. Will the COVID-19 pandemic reduce or accelerate that spending? Sherry Glied, PhD, Dean and Professor of Public Service at New York University, explains. Recorded Monday, April 27, 2020. Read the article The Potential Effects of Coronavirus on National Health Expenditures

Steven M. Bradley, MD, MPH joins JAMA Network editors to discuss a randomized clinical trial evaluating the safety and efficacy of 2 chloroquine diphosphate dosages in patients with severe coronavirus disease 2019 (COVID-19). Read the editorial here: https://ja.ma/2JC5sGx. JNO Live is a weekly broadcast featuring conversations about the latest research being published in JAMA Network Open. Follow us on Facebook, Twitter and YouTube for details on the next broadcast.

A new exhibit on the 1918 flu pandemic asks: What is an individual's responsibility to their community during a pandemic? Exhibit curator Jane Boyd and museum manager Nancy Hill take Jennifer Abbasi on a tour of the medical museum's new exhibit just weeks before the COVID-19 outbreak first emerged. Pandemic Part 1: 1918 Flu Pandemic and COVID-19 Read the article: Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Medical historian Howard Markel, MD, PhD, director of the University of Michigan's Center for the History of Medicine, speaks with JAMA Fishbein fellow Angel Desai, MD, about lessons from the devastating 1918 flu pandemic. Markel discusses his research into the effects of social distancing on US death rates during the worldwide outbreak. Pandemic Part 2: A Trip to Philadelphia’s Mutter Museum Read the article: Twentieth-Century Lessons for a Modern Coronavirus Pandemic

Marc Lipsitch, DPhil, an infectious diseases epidemiologist developing biological and modeling approaches to pathogen transmission and outbreaks, discusses evolution of the COVID-19 pandemic in summer and fall 2020. Originally recorded April 22, 2020.

Management of COVID-19-related respiratory failure differs from what is necessary for ARDS. Rather than having alveolar edema, COVID-19 patients have pulmonary vascular dysregulation. Gas exchange is severely compromised with little reduction in lung compliance. Ventilatory support for COVID-19 patients requires higher than normal tidal volumes with minimal PEEP and allowance for higher than usual serum CO2 levels. How the unique pathophysiology of respiratory failure should be treated is discussed by John J. Marini, MD, professor of medicine at the University of Minnesota.

JAMA Health Forum editors John Ayanian, MD, MPP, and Melinda Buntin, PhD, discuss changes in US health care and health policy driven by the coronavirus pandemic. Recorded April 16, 2020.

Rochelle Walensky, MD, MPH, of Harvard University discusses public health strategies and policies for lifting shelter-in-place and quarantine and for returning the US to a new post-first-wave normal. Recorded Monday April 20, 2020.

New York City coronavirus update from Mitchell Katz, MD, President and CEO of NYC Health + Hospitals, the largest municipal public health system in the United States. Recorded April 13, 2020.

Questions about testing, chloroquine toxicity, duration of immunity and reinfection, and what to expect next are gripping the US as the novel coronavirus spreads. JAMA Associate Editor Preeti Malani, MD, professor of medicine and Chief Health Officer at the University of Michigan, discusses recent developments in a live conversation with JAMA Editor in Chief Howard Bauchner. Recorded on April 6, 2020.

NIAID Director and Presidential Coronavirus Task Force Advisor Anthony Fauci, MD, discusses recent developments in the global COVID-19 pandemic with JAMA Editor Howard Bauchner, MD. Recorded April 8, 2020.

US states are taking the lead in managing the COVID-19 pandemic. What can state governors expect from the federal government and from the US Department of Health and Human Services? Governor Mike Leavitt from Leavitt Partners joins JAMA Editor Howard Bauchner, MD, in this live Q&A. Recorded April 8, 2020.

Shortages of face masks and N95 respirators have forced clinicians and hospitals to reuse these normally disposable items. Ron Shaffer, PhD, former CDC PPE Research Branch Chief, discusses effective sterilization techniques and how to test that the equipment stays protective after sterilization.

Infectious epidemics have always driven change and triggered discrimination in human societies. Frank Snowden, DPhil, Professor Emeritus of History and History of Medicine at Yale University and author of Epidemics and Society: From the Black Death to the Present (Yale University Press, 2019), puts the COVID-19 pandemic in historical context.

Food and medicine shopping is essential during the COVID-19 pandemic, but requires getting out and standing close to strangers at a time when social distancing and sheltering-in-place are recommended to slow spread of disease. David Aronoff, MD, director of the Division of Infectious Diseases at Vanderbilt University in Nashville, explains how to minimize COVID-19 risk while shopping.

Noninvasive ventilation (NIV), working with dying patients’ families, use of experimental therapies, and more. JAMA Associate Editor Derek Angus, MD, MPH, Distinguished Professor and Chair of Critical Care Medicine at the University of Pittsburgh, provides a COVID-19 ICU management update. Watch the recording of this livestream

How does the current pandemic compare to historical infectious outbreaks and what can we expect in summer and fall of 2020? Nicholas Christakis, MD, PhD, MPH, director of the Human Nature Lab, Co-director of the Institute of Network Science, and Sterling Professor of Social and Natural Science at Yale University, discusses the epidemiology of COVID-19.

Interview with Alfred Sommer, MD, author of Humans, Viruses, and the Eye—An Early Report From the COVID-19 Front Line

Interview with Joshua K Tay, author of Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak, and Babak Givi, MD, author of Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic

Hospitals need ways to make rational, fair decisions about who gets ICU beds and ventilators if COVID-19 patients overwhelm capacity. Douglas B. White, MD, MAS, Director of the Program on Ethics and Decision Making in Critical Illness at the University of Pittsburgh, discusses a framework for those decisions and a guideline he helped develop for allocation of scarce resources in public health emergencies.

The lack of availability of COVID-19 testing has interfered with the ability to contain the spread of disease. Omai Garner, PhD, laboratory director for Clinical Microbiology in the UCLA health system, explains how PCR testing for COVID-19 works and why testing is in short supply.

Interview with Robert O. Bonow, MD, Patrick T. O'Gara, MD, Clyde W. Yancy, MD, and Gregg C. Fonarow, MD, authors of Association of Coronavirus Disease 2019 (COVID-19) With Myocardial Injury and Mortality and Ajay J. Kirtane, MD

As COVID-19 spreads globally, populations who survive their illness will become immune. Mayo Vaccine Research Group Director Gregory Poland, MD, discusses antibody responses, duration of immunity, vaccine safety, and the prospects for using convalescent serum to passively immunize people unexposed to SARS-CoV-2.

In 2003, Toronto was the North American center for Severe Acute Respiratory Syndrome (SARS). The disease spread through the city’s hospitals before anyone knew what was happening. Dr Allison McGeer was a clinician caring for SARS patients and ultimately was infected herself. She describes her experience as a patient and provider and reviews lessons learned that might help others manage their regional COVID-19 outbreaks. Related: Supporting the Health Care Workforce During the COVID-19 Global Epidemic

As COVID-19 spreads, clinicians and health systems are struggling to prepare for a surge of patients. Richard Stone, MD, the US Veterans Health Administration's Executive in Charge, spoke with JAMA about how the VA health system is preparing for this public health emergency.

The ARDS in COVID-19 patients appears more responsive to PEEP and prone ventilation, but seems to require prolonged ventilation and may be associated with myocardial injury. Michelle N. Gong, MD, MS, Chief of Critical Care Medicine at Montefiore Medical Center in the Bronx, discusses her department's experience managing critically ill coronavirus patients, procuring diagnostic tests and personal protective equipment (PPE) for her staff, and more.

Chloroquine was shown in 2004 to be active in vitro against SARS coronavirus but is of unproven efficacy and safety in patients infected with SARS-CoV-2. The drug's potential benefits and risks for COVID-19 patients, without and with azithromycin, is discussed by Dr. David Juurlink, head of the Division of Clinical Pharmacology and Toxicology at Sunnybrook Health Sciences Centre in Toronto.

Interview with Jason Ying Kuen Chan, MBBS, author of Practical Aspects of Otolaryngologic Clinical Services During the 2019 Novel Coronavirus Epidemic: An Experience in Hong Kong

Emerging information about how SARS-CoV-2 virus infects cells has led to speculation that NSAIDs and ACE inhibitors/angiotensin receptor blockers (ARBs) may worsen clinical disease. Infectious disease physician Carlos del Rio, MD, of Emory University explains the concerns and their clinical implications.

The strategy for managing the COVID-19 pandemic has shifted from containment to mitigation. What does that mean for US hospitals and health systems? Kaiser Permanente Executive Vice President Stephen M. Parodi, MD, discusses telemedicine, protecting health care workers, equipment allocation planning, and more.

Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD. JAMA Coronavirus Resource Center

Coronavirus testing will help countries manage coronavirus disease 2019 (COVID-19) but will raise questions about how to counsel patients about their test results. The CDC's Deputy Director for Infectious Diseases Jay C. Butler, MD, talks with JAMA Editor Howard Bauchner about what to advise healthy patients with positive PCR results, sick patients with negative test results, exposed health care workers, and more.

Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned included accommodating for significant numbers of staff not available to work in the clinic because of school closures, change in workflow because of shortages of personal protective equipment, physicians having to accommodate very large numbers of patient queries via telephone, email, or electronic health record, and the importance of the rapid development of local ability to test for SARS-CoV-2 independent of public health agencies.

Seattle has been a focal point for the US in the coronavirus pandemic. Doug Paauw, MD, professor of medicine at the University of Washington, in Seattle, describes the UW primary care clinic experience as this pandemic evolved. Major lessons learned included accommodating for significant numbers of staff not available to work in the clinic because of school closures, change in workflow because of shortages of personal protective equipment, physicians having to accommodate very large numbers of patient queries via telephone, email, or electronic health record, and the importance of the rapid development of local ability to test for SARS-CoV-2 independent of public health agencies.

Physicians in Lombardy, Italy, have been overwhelmed by COVID-19 patients requiring critical care. Based on an existing ECMO center network they developed an ICU network to rapidly identify, triage, and manage patients infected with SARS-2-CoV. Maurizio Cecconi, MD, of Humanitas University in Milan discusses the region’s approach to the surge, including clinical and supply management, health care worker training and protection, and ventilation strategies, with JAMA Editor Howard Bauchner. Read the article: Critical Care Utilization for the COVID-19 Outbreak in Lombardy, Italy: Early Experience and Forecast During an Emergency Response

Coronavirus testing, mortality, vaccine development, containment vs mitigation, and more. JAMA Editor Howard Bauchner, MD, interviews US NIAID Director Anthony Fauci, MD, about the latest developments in SARS-CoV-2 science and global spread of infection. JAMA Coronavirus Resource Page

By mid-February 2020 there were 60,000 confirmed cases of COVID-19, the vast majority diagnosed in Hubei Province (including Wuhan city) in mainland China. China CDC Chief Epidemiologist Zunyou Wu, MD, PhD discusses the latest COVID-19 developments in the country with JAMA Editor in Chief Howard Bauchner, MD.

In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner. Coronavirus Resource Center

The 2019 novel coronavirus (2019-nCoV) outbreak exemplifies ongoing biothreats to global security, as each new threat tests principles of preparation and response at national, regional, and clinical levels. Tom Inglesby, MD, director of the Center for Health Security at the Johns Hopkins Bloomberg School of Public Health, discusses biosecurity with Angel Desai, MD, JAMA Fishbein fellow.

Interview with Anthony S. Fauci, MD, author of Coronavirus Infections—More Than Just the Common Cold